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Conserved domains on  [gi|197107113|pdb|2K53|A]
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Chain A, A3DK08 Protein

Protein Classification

DUF1858 domain-containing protein( domain architecture ID 10024265)

DUF1858 domain-containing protein may contain a hybrid cluster protein-associated redox disulfide

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
prismane_assoc TIGR03980
hybrid cluster protein-associated redox disulfide domain; Members of this protein family ...
 3-60 1.77e-29

hybrid cluster protein-associated redox disulfide domain; Members of this protein family resemble the domain of unknown function DUF1858 described by pfam08984, but all members contain an apparent redox-active disulfide. In at least one member protein, a cysteine in the CXXC motif is substituted by a selenocysteine. Most member proteins consist of this domain only, but a few members are fused to or adjacent to members of the hybrid-cluster (prismane) family or the nitrite/sulfite reductase family. [Energy metabolism, Electron transport]


:

Pssm-ID: 274898 [Multi-domain]  Cd Length: 58  Bit Score: 98.74  E-value: 1.77e-29
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
2K53_A         3 ITKDMIIADVLQMDRGTAPIFINNGMHCLGCPSSMGESIEDACAVHGIDADKLVKELN 60
Cdd:TIGR03980  1 ITKDMTIGEILRKYPETAEVFMRFGMHCVGCPSAQFETLEEAAMVHGIDVDELLEELN 58
 
Name Accession Description Interval E-value
prismane_assoc TIGR03980
hybrid cluster protein-associated redox disulfide domain; Members of this protein family ...
 3-60 1.77e-29

hybrid cluster protein-associated redox disulfide domain; Members of this protein family resemble the domain of unknown function DUF1858 described by pfam08984, but all members contain an apparent redox-active disulfide. In at least one member protein, a cysteine in the CXXC motif is substituted by a selenocysteine. Most member proteins consist of this domain only, but a few members are fused to or adjacent to members of the hybrid-cluster (prismane) family or the nitrite/sulfite reductase family. [Energy metabolism, Electron transport]


Pssm-ID: 274898 [Multi-domain]  Cd Length: 58  Bit Score: 98.74  E-value: 1.77e-29
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
2K53_A         3 ITKDMIIADVLQMDRGTAPIFINNGMHCLGCPSSMGESIEDACAVHGIDADKLVKELN 60
Cdd:TIGR03980  1 ITKDMTIGEILRKYPETAEVFMRFGMHCVGCPSAQFETLEEAAMVHGIDVDELLEELN 58
DUF1858 pfam08984
Domain of unknown function (DUF1858); This domain has no known function. It is found in ...
 5-56 8.95e-16

Domain of unknown function (DUF1858); This domain has no known function. It is found in various hypothetical bacterial proteins.


Pssm-ID: 462648  Cd Length: 57  Bit Score: 64.09  E-value: 8.95e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
2K53_A         5 KDMIIADVLQMDRGTAPIFINNGMHCLGCPS-----SMGESIEDACAVHGIDADKLV 56
Cdd:pfam08984  1 KDMTIGELLEKYPELIEILVELGFHCLGCPIlrktvARFETLEQAAKVHGIDLDELI 57
RIC COG2846
Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains ...
 1-67 1.78e-05

Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442094 [Multi-domain]  Cd Length: 237  Bit Score: 40.25  E-value: 1.78e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
2K53_A        1 MKITKDMIIADVLQMDRGTAPIFINNGM--HCLGcpssmGESIEDACAVHGIDADKLVKELNEYFEKKE 67
Cdd:COG2846   4 LTITPDQTVGDLVAENPGAAAVFRRFGIdfCCGG-----DRSLAEACEEKGLDPEELLAELNALANEEE 67
 
Name Accession Description Interval E-value
prismane_assoc TIGR03980
hybrid cluster protein-associated redox disulfide domain; Members of this protein family ...
 3-60 1.77e-29

hybrid cluster protein-associated redox disulfide domain; Members of this protein family resemble the domain of unknown function DUF1858 described by pfam08984, but all members contain an apparent redox-active disulfide. In at least one member protein, a cysteine in the CXXC motif is substituted by a selenocysteine. Most member proteins consist of this domain only, but a few members are fused to or adjacent to members of the hybrid-cluster (prismane) family or the nitrite/sulfite reductase family. [Energy metabolism, Electron transport]


Pssm-ID: 274898 [Multi-domain]  Cd Length: 58  Bit Score: 98.74  E-value: 1.77e-29
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
2K53_A         3 ITKDMIIADVLQMDRGTAPIFINNGMHCLGCPSSMGESIEDACAVHGIDADKLVKELN 60
Cdd:TIGR03980  1 ITKDMTIGEILRKYPETAEVFMRFGMHCVGCPSAQFETLEEAAMVHGIDVDELLEELN 58
DUF1858 pfam08984
Domain of unknown function (DUF1858); This domain has no known function. It is found in ...
 5-56 8.95e-16

Domain of unknown function (DUF1858); This domain has no known function. It is found in various hypothetical bacterial proteins.


Pssm-ID: 462648  Cd Length: 57  Bit Score: 64.09  E-value: 8.95e-16
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
2K53_A         5 KDMIIADVLQMDRGTAPIFINNGMHCLGCPS-----SMGESIEDACAVHGIDADKLV 56
Cdd:pfam08984  1 KDMTIGELLEKYPELIEILVELGFHCLGCPIlrktvARFETLEQAAKVHGIDLDELI 57
RIC COG2846
Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains ...
 1-67 1.78e-05

Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442094 [Multi-domain]  Cd Length: 237  Bit Score: 40.25  E-value: 1.78e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
2K53_A        1 MKITKDMIIADVLQMDRGTAPIFINNGM--HCLGcpssmGESIEDACAVHGIDADKLVKELNEYFEKKE 67
Cdd:COG2846   4 LTITPDQTVGDLVAENPGAAAVFRRFGIdfCCGG-----DRSLAEACEEKGLDPEELLAELNALANEEE 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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