NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|157834945|pdb|2EZC|A]
View 

Chain A, PHOSPHOTRANSFERASE SYSTEM, ENZYME I

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK11177 super family cl32654
phosphoenolpyruvate-protein phosphotransferase PtsI;
1-258 2.11e-171

phosphoenolpyruvate-protein phosphotransferase PtsI;


The actual alignment was detected with superfamily member PRK11177:

Pssm-ID: 183017 [Multi-domain]  Cd Length: 575  Bit Score: 484.90  E-value: 2.11e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         1 MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL 80
Cdd:PRK11177   1 MISGILASPGIAFGKALLLKEDEIVINRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        81 EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA 160
Cdd:PRK11177  81 EDEELEQEIIALIKDKHMTADAAAHSVIEGQAKALEELDDEYLKERAADVRDIGKRLLKNILGLKIIDLSAIQEEVILVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       161 ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR 240
Cdd:PRK11177 161 ADLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELK 240

                        250
                 ....*....|....*...
2EZC_A       241 AVQEQVASEKAELAKLKD 258
Cdd:PRK11177 241 AVQEQYASEKAELAKLKD 258
 
Name Accession Description Interval E-value
PRK11177 PRK11177
phosphoenolpyruvate-protein phosphotransferase PtsI;
1-258 2.11e-171

phosphoenolpyruvate-protein phosphotransferase PtsI;


Pssm-ID: 183017 [Multi-domain]  Cd Length: 575  Bit Score: 484.90  E-value: 2.11e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         1 MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL 80
Cdd:PRK11177   1 MISGILASPGIAFGKALLLKEDEIVINRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        81 EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA 160
Cdd:PRK11177  81 EDEELEQEIIALIKDKHMTADAAAHSVIEGQAKALEELDDEYLKERAADVRDIGKRLLKNILGLKIIDLSAIQEEVILVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       161 ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR 240
Cdd:PRK11177 161 ADLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELK 240

                        250
                 ....*....|....*...
2EZC_A       241 AVQEQVASEKAELAKLKD 258
Cdd:PRK11177 241 AVQEQYASEKAELAKLKD 258
PTS_I_fam TIGR01417
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ...
 2-259 8.57e-117

phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.


Pssm-ID: 273611 [Multi-domain]  Cd Length: 565  Bit Score: 345.62  E-value: 8.57e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A          2 ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLE 81
Cdd:TIGR01417   1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         82 DEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAA 161
Cdd:TIGR01417  81 DPELTEEVIELIKKDHKNAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDLSEIQDEVILVAE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        162 DLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRA 241
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240

                         250
                  ....*....|....*...
2EZC_A        242 VQEQVASEKAELAKLKDR 259
Cdd:TIGR01417 241 KQEAVSSEKAELAKLKDK 258
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 2-258 3.04e-109

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 326.26  E-value: 3.04e-109
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        2 ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLE 81
Cdd:COG1080   1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       82 DEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAA 161
Cdd:COG1080  81 DPELIEEVEELIREGRYNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLSDLPEPVILVAH 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A      162 DLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRA 241
Cdd:COG1080 161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNPDEETLAEYRE 240

                       250
                ....*....|....*..
2EZC_A      242 VQEQVASEKAELAKLKD 258
Cdd:COG1080 241 RQAEYAAERAELARLRD 257
PEP-utilizers_N pfam05524
PEP-utilizing enzyme, N-terminal;
3-126 8.62e-30

PEP-utilizing enzyme, N-terminal;


Pssm-ID: 461671 [Multi-domain]  Cd Length: 125  Bit Score: 108.47  E-value: 8.62e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A          3 SGILASPGIAFGKALLLKEDEIVI-DRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLE 81
Cdd:pfam05524   1 KGIGASPGIAIGKAVVLEEPELEVpDEREVPADDVEAEIARLEAALEAAREELEALAERAAGELGEEEAAIFEAHLMMLE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
2EZC_A         82 DEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKER 126
Cdd:pfam05524  81 DPELLEEVEELIREGGLNAEAAVKEVVDEFAAMFEAMDDPYLRER 125
 
Name Accession Description Interval E-value
PRK11177 PRK11177
phosphoenolpyruvate-protein phosphotransferase PtsI;
1-258 2.11e-171

phosphoenolpyruvate-protein phosphotransferase PtsI;


Pssm-ID: 183017 [Multi-domain]  Cd Length: 575  Bit Score: 484.90  E-value: 2.11e-171
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         1 MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL 80
Cdd:PRK11177   1 MISGILASPGIAFGKALLLKEDEIVINRKKISADQVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        81 EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA 160
Cdd:PRK11177  81 EDEELEQEIIALIKDKHMTADAAAHSVIEGQAKALEELDDEYLKERAADVRDIGKRLLKNILGLKIIDLSAIQEEVILVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       161 ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR 240
Cdd:PRK11177 161 ADLTPSETAQLNLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNITKQVKNGDYLILDAVNNQIYVNPTNEVIEELK 240

                        250
                 ....*....|....*...
2EZC_A       241 AVQEQVASEKAELAKLKD 258
Cdd:PRK11177 241 AVQEQYASEKAELAKLKD 258
PTS_I_fam TIGR01417
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ...
 2-259 8.57e-117

phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.


Pssm-ID: 273611 [Multi-domain]  Cd Length: 565  Bit Score: 345.62  E-value: 8.57e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A          2 ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLE 81
Cdd:TIGR01417   1 ISGIGVSPGIAIGKALLLKKPDLVIDRKKISASQVDQEISRFLSARAKAKEDLETIKTKAGKTFGQEKAAIFEAHILILE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         82 DEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAA 161
Cdd:TIGR01417  81 DPELTEEVIELIKKDHKNAEFAAHEVFEGQAKSLEEMDDEYLKERAADIRDIGNRLLGHLLGVKISDLSEIQDEVILVAE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        162 DLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRA 241
Cdd:TIGR01417 161 DLTPSETAQLNLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSVTSQVKNGDTVIIDGVKGIVIFNPSSETIDKYEA 240

                         250
                  ....*....|....*...
2EZC_A        242 VQEQVASEKAELAKLKDR 259
Cdd:TIGR01417 241 KQEAVSSEKAELAKLKDK 258
PtsA COG1080
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ...
 2-258 3.04e-109

Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];


Pssm-ID: 440698 [Multi-domain]  Cd Length: 571  Bit Score: 326.26  E-value: 3.04e-109
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        2 ISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLE 81
Cdd:COG1080   1 LKGIAASPGIAIGKAFLLREEDLEVPEYTISPEDVEAEIARLEAALAKAREELEALREKAPEDLGEEEAAIFDAHLLLLE 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       82 DEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVAA 161
Cdd:COG1080  81 DPELIEEVEELIREGRYNAEWALKEVIEELAAQFEALDDEYLRERAADIRDVGRRVLRNLLGVEAPDLSDLPEPVILVAH 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A      162 DLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMRA 241
Cdd:COG1080 161 DLTPSDTAQLDPSRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIVDGDAGVVIVNPDEETLAEYRE 240

                       250
                ....*....|....*..
2EZC_A      242 VQEQVASEKAELAKLKD 258
Cdd:COG1080 241 RQAEYAAERAELARLRD 257
PEP-utilizers_N pfam05524
PEP-utilizing enzyme, N-terminal;
3-126 8.62e-30

PEP-utilizing enzyme, N-terminal;


Pssm-ID: 461671 [Multi-domain]  Cd Length: 125  Bit Score: 108.47  E-value: 8.62e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A          3 SGILASPGIAFGKALLLKEDEIVI-DRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLE 81
Cdd:pfam05524   1 KGIGASPGIAIGKAVVLEEPELEVpDEREVPADDVEAEIARLEAALEAAREELEALAERAAGELGEEEAAIFEAHLMMLE 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
2EZC_A         82 DEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKER 126
Cdd:pfam05524  81 DPELLEEVEELIREGGLNAEAAVKEVVDEFAAMFEAMDDPYLRER 125
PRK11377 PRK11377
dihydroxyacetone kinase subunit M; Provisional
 1-223 5.43e-28

dihydroxyacetone kinase subunit M; Provisional


Pssm-ID: 183108 [Multi-domain]  Cd Length: 473  Bit Score: 111.38  E-value: 5.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         1 MISGILASPGIAFGKALLLKEDEIVIDRKkiSADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL 80
Cdd:PRK11377 246 APPTLRPVPSPVSGKAFYYQPVLCTVQAK--STLTVEEEQERLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLL 323

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        81 EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKiIDLSAIQDEVILVA 160
Cdd:PRK11377 324 DDPELLAAASERLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTK-EELPQFNSPTILLA 402

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
2EZC_A       161 ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAV 223
Cdd:PRK11377 403 ENIYPSTVLQLDPAVVKGICLSAGSPLSHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVK 465
PEP-utilizers pfam00391
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ...
 151-222 1.58e-24

PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.


Pssm-ID: 459796 [Multi-domain]  Cd Length: 73  Bit Score: 92.86  E-value: 1.58e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
2EZC_A        151 AIQDEVILVAADLTPSETAQLnlKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDA 222
Cdd:pfam00391   1 KLPEGVILVAPDTTPSDTAGL--DKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDG 70
PRK11061 PRK11061
phosphoenolpyruvate--protein phosphotransferase;
2-256 4.06e-21

phosphoenolpyruvate--protein phosphotransferase;


Pssm-ID: 182937 [Multi-domain]  Cd Length: 748  Bit Score: 92.36  E-value: 4.06e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A         2 ISGILASPGIAFGKALLlkedeiviDRKKISADQV--------DQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIF 73
Cdd:PRK11061 171 IRALPASPGVAIAEGWQ--------DATQPLLEQVypastldpALERERLTGALEEAANEFRRYSKRFAAGAQKETAAIF 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A        74 EGHIMLLEDEELEQEIIALIkDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNiLGLKIIDLSAIQ 153
Cdd:PRK11061 243 DLYSHLLNDPRLRRELFAEV-DKGSVAEWAVKQVIEKFAEQFAALSDNYLRERAGDLRALGQRLLFH-LDDSEQGPNAWP 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       154 DEVILVAADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVkNDDYLILDAVNNQVYVNPtN 233
Cdd:PRK11061 321 ERFILVADELTATLLAELPQDRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLL-HQRLLIVDGYRGELLVDP-E 398

                        250       260
                 ....*....|....*....|....*
2EZC_A       234 EVIdkmraVQE--QVASEKAELAKL 256
Cdd:PRK11061 399 PVL-----LQEyqRLISEEIELSRL 418
PRK08296 PRK08296
hypothetical protein; Provisional
 148-221 4.20e-11

hypothetical protein; Provisional


Pssm-ID: 181362  Cd Length: 603  Bit Score: 62.75  E-value: 4.20e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
2EZC_A       148 DLSAIQDEVILVAADLTPSETAQLnlKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILD 221
Cdd:PRK08296 522 ELSEVQEGEILVCPVTSPSWAPIF--AKIKATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRLRVD 593
PpsA COG0574
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ...
 148-222 1.21e-10

Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis


Pssm-ID: 440339 [Multi-domain]  Cd Length: 455  Bit Score: 61.00  E-value: 1.21e-10
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
2EZC_A      148 DLSAIQDEVILVAADLTPSETAqlNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDA 222
Cdd:COG0574 377 ELARFQEGVILVRDETDPDDVP--GMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITVDG 449
PRK06464 PRK06464
phosphoenolpyruvate synthase; Validated
 145-216 1.22e-08

phosphoenolpyruvate synthase; Validated


Pssm-ID: 235809 [Multi-domain]  Cd Length: 795  Bit Score: 55.14  E-value: 1.22e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
2EZC_A       145 KII----DLSAIQDEVILVAADLTPS-ETAqlnLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDD 216
Cdd:PRK06464 372 RVIldisEMDKVQPGDVLVTDMTDPDwEPV---MKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQ 445
PykA2 COG3848
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
148-228 1.25e-07

Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];


Pssm-ID: 443058  Cd Length: 321  Bit Score: 51.44  E-value: 1.25e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A      148 DLSAIQDEVILVAADLTPSETAQLnlKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQV 227
Cdd:COG3848 236 ALEKFEEGDILVVPSTDAEFVPAI--EKAAGIITEEGGLTSHAAIVGLELGIPVIVGAEGATEILKDGQVVTVDAERGVV 313


                .
2EZC_A      228 Y 228
Cdd:COG3848 314 Y 314
PRK06354 PRK06354
pyruvate kinase; Provisional
 148-228 6.11e-06

pyruvate kinase; Provisional


Pssm-ID: 235784 [Multi-domain]  Cd Length: 590  Bit Score: 46.84  E-value: 6.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2EZC_A       148 DLSAIQDEVILVA----ADLTPSetaqlnLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAV 223
Cdd:PRK06354 505 EVAKVNEGDILVTpstdADMIPA------IEKAAAIITEEGGLTSHAAVVGLRLGIPVIVGVKNATSLIKDGQIITVDAA 578


                 ....*
2EZC_A       224 NNQVY 228
Cdd:PRK06354 579 RGVVY 583
PRK05849 PRK05849
hypothetical protein; Provisional
 174-229 1.83e-04

hypothetical protein; Provisional


Pssm-ID: 235623 [Multi-domain]  Cd Length: 783  Bit Score: 42.66  E-value: 1.83e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
2EZC_A       174 KKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVT-SQVKNDDYLILDAVNNQVYV 229
Cdd:PRK05849 726 KGIAGLITCYGGANSHMAIRAAELGLPAVIGVGEELfEKWLKAKRILLDCASQRIEI 782
PRK06241 PRK06241
phosphoenolpyruvate synthase; Validated
 157-221 2.22e-04

phosphoenolpyruvate synthase; Validated


Pssm-ID: 235751 [Multi-domain]  Cd Length: 871  Bit Score: 42.18  E-value: 2.22e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
2EZC_A       157 ILVAADLTPSETAQLNLKKvlGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILD 221
Cdd:PRK06241 798 ILVTAFTDPGWTPLFVSIK--GLVTEVGGLMTHGAVIAREYGIPAVVGVENATKLIKDGQRIRVD 860
PRK05878 PRK05878
pyruvate phosphate dikinase; Provisional
 156-206 6.93e-03

pyruvate phosphate dikinase; Provisional


Pssm-ID: 235635 [Multi-domain]  Cd Length: 530  Bit Score: 37.42  E-value: 6.93e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
2EZC_A       156 VILVAADLTPSETAQLNLkkVLGFITDAGGRTSHTSIMARSLELPAIVGTG 206
Cdd:PRK05878 382 VILVRDHTRPDDVHGMLA--AQGIVTEVGGATSHAAVVSRELGRVAVVGCG 430
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH