|
Name |
Accession |
Description |
Interval |
E-value |
| COesterase |
pfam00135 |
Carboxylesterase family; |
4-528 |
0e+00 |
|
Carboxylesterase family;
Pssm-ID: 395084 [Multi-domain] Cd Length: 513 Bit Score: 634.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 4 SPPVVDTVHGKVLGKFVSLEGFaQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQllself 83
Cdd:pfam00135 1 DSPVVTTSLGRVRGKRLKVDGG-KPVYAFLGIPYAEPPVGELRFQPPEPPEPWTGVRDATKFGPRCPQNGDLTS------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 84 tnrKENIPLKLSEDCLYLNIYTPADLTK-KNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 162
Cdd:pfam00135 74 ---PGSSGLEGSEDCLYLNVYTPKELKEnKNKLPVMVWIHGGGFMFGSGSLYDGSYLAAEGDVIVVTINYRLGPLGFLST 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 163 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 242
Cdd:pfam00135 151 GDDEAPGNYGLLDQVLALRWVQENIASFGGDPNRVTLFGESAGAASVSLLLLSPLSKGLFHRAILMSGSALSPWAIQSNA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 243 VKpLAEQIAITAGCKTTTSAVMVHCLRQKTEeellettlkMKFLSLDLQGDPRESQPLL--GTVIDGMLLLKTPEELQAE 320
Cdd:pfam00135 231 RQ-RAKELAKLVGCPTSDSAELVECLRSKPA---------EELLDAQLKLLVYGSVPFVpfGPVVDGDFLPEHPEELLKS 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 321 RNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAK--ELIPEATEKYL--GGTDDTVKKKD 396
Cdd:pfam00135 301 GNFPKVPLLIGVTKDEGLLFAAYILDNVDILKALEEKLLRSLLIDLLYLLLVDLpeEISAALREEYLdwGDRDDPETSRR 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 397 LFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSsdMKPKTVIGDHGDELFSVFGAPFL-KEGASEEEIRLSK 475
Cdd:pfam00135 381 ALVELLTDYLFNCPVIRFADLHASRGTPVYMYSFDYRGSSL--RYPKWVGVDHGDELPYVFGTPFVgALLFTEEDEKLSR 458
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
2DR0_B 476 MVMKFWANFARNGNPNG-EGLPHWPEYNQKEG-YLQIGANTQAAQKLKDKEVAFW 528
Cdd:pfam00135 459 KMMTYWTNFAKTGNPNGpEGLPKWPPYTDENGqYLSIDLEPRVKQGLKAERCAFW 513
|
|
| Esterase_lipase |
cd00312 |
Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on ... |
7-519 |
0e+00 |
|
Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate.
Pssm-ID: 238191 [Multi-domain] Cd Length: 493 Bit Score: 595.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 7 VVDTVHGKVLGKFVSlegfaqPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLselftnr 86
Cdd:cd00312 1 LVVTPNGKVRGVDEG------GVYSFLGIPYAEPPVGDLRFKEPQPYEPWSDVLDATSYPPSCMQWDQLGGGL------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 87 kENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAA-HENVVVVTIQYRLGIWGFFSTGDE 165
Cdd:cd00312 68 -WNAKLPGSEDCLYLNVYTPKNTKPGNSLPVMVWIHGGGFMFGSGSLYPGDGLAReGDNVIVVSINYRLGVLGFLSTGDI 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 166 HSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGdVKP 245
Cdd:cd00312 147 ELPGNYGLKDQRLALKWVQDNIAAFGGDPDSVTIFGESAGGASVSLLLLSPDSKGLFHRAISQSGSALSPWAIQEN-ARG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 246 LAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGdpresqpLLGTVIDGMLLLKTPEELQAERNFHT 325
Cdd:cd00312 226 RAKRLARLLGCNDTSSAELLDCLRSKSAEELLDATRKLLLFSYSPFL-------PFGPVVDGDFIPDDPEELIKEGKFAK 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 326 VPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLwkSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV 405
Cdd:cd00312 299 VPLIIGVTKDEGGYFAAMLLNFDAKLIIETNDRWLELL--PYLLFYADDALADKVLEKYPGDVDDSVESRKNLSDMLTDL 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 406 MFGVPSVIVARNHRDA-GAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANF 484
Cdd:cd00312 377 LFKCPARYFLAQHRKAgGSPVYAYVFDHRSSLSVGRWPPWLGTVHGDEIFFVFGNPLLKEGLREEEEKLSRTMMKYWANF 456
|
490 500 510
....*....|....*....|....*....|....*..
2DR0_B 485 ARNGNPNGEG-LPHWPEYN-QKEGYLQIGANTQAAQK 519
Cdd:cd00312 457 AKTGNPNTEGnLVVWPAYTsESEKYLDINIEGTEIKQ 493
|
|
| PnbA |
COG2272 |
Carboxylesterase type B [Lipid transport and metabolism]; |
1-532 |
1.39e-155 |
|
Carboxylesterase type B [Lipid transport and metabolism];
Pssm-ID: 441873 Cd Length: 500 Bit Score: 453.58 E-value: 1.39e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 1 HPSSPPVVDTVHGKVLGkfVSLEGfaqpVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLS 80
Cdd:COG2272 8 AAAAAPVVRTEAGRVRG--VVEGG----VRVFLGIPYAAPPVGELRWRAPQPVEPWTGVRDATEFGPACPQPPRPGDPGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 81 elftnrkeniPLKLSEDCLYLNIYTPADLTKKnRLPVMVWIHGGGLMVGAAST--YDGLALAAhENVVVVTIQYRLGIWG 158
Cdd:COG2272 82 ----------PAPGSEDCLYLNVWTPALAAGA-KLPVMVWIHGGGFVSGSGSEplYDGAALAR-RGVVVVTINYRLGALG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 159 FF-----STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVAL 233
Cdd:COG2272 150 FLalpalSGESYGASGNYGLLDQIAALRWVRDNIAAFGGDPDNVTIFGESAGAASVAALLASPLAKGLFHRAIAQSGAGL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 234 TsvLVKKGDVKPLAEQIAITAGCKTTTSAvmvhCLRQKTEEellettlkmKFLSLDLQGDPRESQPL-LGTVIDGMLLLK 312
Cdd:COG2272 230 S--VLTLAEAEAVGAAFAAALGVAPATLA----ALRALPAE---------ELLAAQAALAAEGPGGLpFGPVVDGDVLPE 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 313 TPEELQAERNFHTVPYMVGINKQEFGWLIPML-MSYPLSEGQLDQktamsLLWKSYPlvciakELIPEATEKYLGGTDdt 391
Cdd:COG2272 295 DPLEAFAAGRAADVPLLIGTNRDEGRLFAALLgDLGPLTAADYRA-----ALRRRFG------DDADEVLAAYPAASP-- 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 392 vkkKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVigdHGDELFSVFG--APFLKEGASEE 469
Cdd:COG2272 362 ---AEALAALATDRVFRCPARRLAEAHAAAGAPVYLYRFDWRSPPLRGFGLGAF---HGAELPFVFGnlDAPALTGLTPA 435
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
2DR0_B 470 EIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEG-YLQIGANTQAAQKLKDKE-VAFWTNLF 532
Cdd:COG2272 436 DRALSDQMQAYWVNFARTGDPNGPGLPEWPAYDPEDRaVMVFDAEPRVVNDPDAEErLDLWDGVV 500
|
|
| PRK10162 |
PRK10162 |
acetyl esterase; |
117-205 |
1.10e-04 |
|
acetyl esterase;
Pssm-ID: 236660 [Multi-domain] Cd Length: 318 Bit Score: 44.32 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 117 VMVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSrgnwghldqVAALRWVQDNIASFGGNP 194
Cdd:PRK10162 83 TLFYLHGGGFILGNLDTHDRIMrlLASYSGCTVIGIDYTLSPEARFPQAIEEI---------VAVCCYFHQHAEDYGINM 153
|
90
....*....|.
2DR0_B 195 GSVTIFGESAG 205
Cdd:PRK10162 154 SRIGFAGDSAG 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COesterase |
pfam00135 |
Carboxylesterase family; |
4-528 |
0e+00 |
|
Carboxylesterase family;
Pssm-ID: 395084 [Multi-domain] Cd Length: 513 Bit Score: 634.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 4 SPPVVDTVHGKVLGKFVSLEGFaQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQllself 83
Cdd:pfam00135 1 DSPVVTTSLGRVRGKRLKVDGG-KPVYAFLGIPYAEPPVGELRFQPPEPPEPWTGVRDATKFGPRCPQNGDLTS------ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 84 tnrKENIPLKLSEDCLYLNIYTPADLTK-KNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 162
Cdd:pfam00135 74 ---PGSSGLEGSEDCLYLNVYTPKELKEnKNKLPVMVWIHGGGFMFGSGSLYDGSYLAAEGDVIVVTINYRLGPLGFLST 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 163 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 242
Cdd:pfam00135 151 GDDEAPGNYGLLDQVLALRWVQENIASFGGDPNRVTLFGESAGAASVSLLLLSPLSKGLFHRAILMSGSALSPWAIQSNA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 243 VKpLAEQIAITAGCKTTTSAVMVHCLRQKTEeellettlkMKFLSLDLQGDPRESQPLL--GTVIDGMLLLKTPEELQAE 320
Cdd:pfam00135 231 RQ-RAKELAKLVGCPTSDSAELVECLRSKPA---------EELLDAQLKLLVYGSVPFVpfGPVVDGDFLPEHPEELLKS 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 321 RNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAK--ELIPEATEKYL--GGTDDTVKKKD 396
Cdd:pfam00135 301 GNFPKVPLLIGVTKDEGLLFAAYILDNVDILKALEEKLLRSLLIDLLYLLLVDLpeEISAALREEYLdwGDRDDPETSRR 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 397 LFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSsdMKPKTVIGDHGDELFSVFGAPFL-KEGASEEEIRLSK 475
Cdd:pfam00135 381 ALVELLTDYLFNCPVIRFADLHASRGTPVYMYSFDYRGSSL--RYPKWVGVDHGDELPYVFGTPFVgALLFTEEDEKLSR 458
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
2DR0_B 476 MVMKFWANFARNGNPNG-EGLPHWPEYNQKEG-YLQIGANTQAAQKLKDKEVAFW 528
Cdd:pfam00135 459 KMMTYWTNFAKTGNPNGpEGLPKWPPYTDENGqYLSIDLEPRVKQGLKAERCAFW 513
|
|
| Esterase_lipase |
cd00312 |
Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on ... |
7-519 |
0e+00 |
|
Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate.
Pssm-ID: 238191 [Multi-domain] Cd Length: 493 Bit Score: 595.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 7 VVDTVHGKVLGKFVSlegfaqPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLselftnr 86
Cdd:cd00312 1 LVVTPNGKVRGVDEG------GVYSFLGIPYAEPPVGDLRFKEPQPYEPWSDVLDATSYPPSCMQWDQLGGGL------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 87 kENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAA-HENVVVVTIQYRLGIWGFFSTGDE 165
Cdd:cd00312 68 -WNAKLPGSEDCLYLNVYTPKNTKPGNSLPVMVWIHGGGFMFGSGSLYPGDGLAReGDNVIVVSINYRLGVLGFLSTGDI 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 166 HSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGdVKP 245
Cdd:cd00312 147 ELPGNYGLKDQRLALKWVQDNIAAFGGDPDSVTIFGESAGGASVSLLLLSPDSKGLFHRAISQSGSALSPWAIQEN-ARG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 246 LAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGdpresqpLLGTVIDGMLLLKTPEELQAERNFHT 325
Cdd:cd00312 226 RAKRLARLLGCNDTSSAELLDCLRSKSAEELLDATRKLLLFSYSPFL-------PFGPVVDGDFIPDDPEELIKEGKFAK 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 326 VPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLwkSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADV 405
Cdd:cd00312 299 VPLIIGVTKDEGGYFAAMLLNFDAKLIIETNDRWLELL--PYLLFYADDALADKVLEKYPGDVDDSVESRKNLSDMLTDL 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 406 MFGVPSVIVARNHRDA-GAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANF 484
Cdd:cd00312 377 LFKCPARYFLAQHRKAgGSPVYAYVFDHRSSLSVGRWPPWLGTVHGDEIFFVFGNPLLKEGLREEEEKLSRTMMKYWANF 456
|
490 500 510
....*....|....*....|....*....|....*..
2DR0_B 485 ARNGNPNGEG-LPHWPEYN-QKEGYLQIGANTQAAQK 519
Cdd:cd00312 457 AKTGNPNTEGnLVVWPAYTsESEKYLDINIEGTEIKQ 493
|
|
| PnbA |
COG2272 |
Carboxylesterase type B [Lipid transport and metabolism]; |
1-532 |
1.39e-155 |
|
Carboxylesterase type B [Lipid transport and metabolism];
Pssm-ID: 441873 Cd Length: 500 Bit Score: 453.58 E-value: 1.39e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 1 HPSSPPVVDTVHGKVLGkfVSLEGfaqpVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLS 80
Cdd:COG2272 8 AAAAAPVVRTEAGRVRG--VVEGG----VRVFLGIPYAAPPVGELRWRAPQPVEPWTGVRDATEFGPACPQPPRPGDPGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 81 elftnrkeniPLKLSEDCLYLNIYTPADLTKKnRLPVMVWIHGGGLMVGAAST--YDGLALAAhENVVVVTIQYRLGIWG 158
Cdd:COG2272 82 ----------PAPGSEDCLYLNVWTPALAAGA-KLPVMVWIHGGGFVSGSGSEplYDGAALAR-RGVVVVTINYRLGALG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 159 FF-----STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVAL 233
Cdd:COG2272 150 FLalpalSGESYGASGNYGLLDQIAALRWVRDNIAAFGGDPDNVTIFGESAGAASVAALLASPLAKGLFHRAIAQSGAGL 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 234 TsvLVKKGDVKPLAEQIAITAGCKTTTSAvmvhCLRQKTEEellettlkmKFLSLDLQGDPRESQPL-LGTVIDGMLLLK 312
Cdd:COG2272 230 S--VLTLAEAEAVGAAFAAALGVAPATLA----ALRALPAE---------ELLAAQAALAAEGPGGLpFGPVVDGDVLPE 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 313 TPEELQAERNFHTVPYMVGINKQEFGWLIPML-MSYPLSEGQLDQktamsLLWKSYPlvciakELIPEATEKYLGGTDdt 391
Cdd:COG2272 295 DPLEAFAAGRAADVPLLIGTNRDEGRLFAALLgDLGPLTAADYRA-----ALRRRFG------DDADEVLAAYPAASP-- 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 392 vkkKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVigdHGDELFSVFG--APFLKEGASEE 469
Cdd:COG2272 362 ---AEALAALATDRVFRCPARRLAEAHAAAGAPVYLYRFDWRSPPLRGFGLGAF---HGAELPFVFGnlDAPALTGLTPA 435
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
2DR0_B 470 EIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEG-YLQIGANTQAAQKLKDKE-VAFWTNLF 532
Cdd:COG2272 436 DRALSDQMQAYWVNFARTGDPNGPGLPEWPAYDPEDRaVMVFDAEPRVVNDPDAEErLDLWDGVV 500
|
|
| Aes |
COG0657 |
Acetyl esterase/lipase [Lipid transport and metabolism]; |
103-206 |
1.13e-20 |
|
Acetyl esterase/lipase [Lipid transport and metabolism];
Pssm-ID: 440422 [Multi-domain] Cd Length: 207 Bit Score: 90.32 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 103 IYTPADLTKKnrLPVMVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGiwgffstgDEHSrgnW-GHLDQV-A 178
Cdd:COG0657 3 VYRPAGAKGP--LPVVVYFHGGGWVSGSKDTHDPLArrLAARAGAAVVSVDYRLA--------PEHP---FpAALEDAyA 69
|
90 100
....*....|....*....|....*...
2DR0_B 179 ALRWVQDNIASFGGNPGSVTIFGESAGG 206
Cdd:COG0657 70 ALRWLRANAAELGIDPDRIAVAGDSAGG 97
|
|
| Abhydrolase_3 |
pfam07859 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
118-206 |
1.50e-14 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 400284 [Multi-domain] Cd Length: 208 Bit Score: 72.63 E-value: 1.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 118 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLgiwgffstGDEHSrgnW--GHLDQVAALRWVQDNIASFGGN 193
Cdd:pfam07859 1 LVYFHGGGFVLGSADTHDRLCrrLAAEAGAVVVSVDYRL--------APEHP---FpaAYDDAYAALRWLAEQAAELGAD 69
|
90
....*....|...
2DR0_B 194 PGSVTIFGESAGG 206
Cdd:pfam07859 70 PSRIAVAGDSAGG 82
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
103-232 |
2.34e-10 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 60.80 E-value: 2.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 103 IYTPADltkKNRLPVMVWIHGGGlmVGAASTYDGLALAAHEN-VVVVTIQYRlgiwgffstGDEHSRGNWGHL---DQVA 178
Cdd:COG1506 14 LYLPAD---GKKYPVVVYVHGGP--GSRDDSFLPLAQALASRgYAVLAPDYR---------GYGESAGDWGGDevdDVLA 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
2DR0_B 179 ALRWVqdnIASFGGNPGSVTIFGESAGGesVSVLVLSPLAKNLFHRAISESGVA 232
Cdd:COG1506 80 AIDYL---AARPYVDPDRIGIYGHSYGG--YMALLAAARHPDRFKAAVALAGVS 128
|
|
| BD-FAE |
pfam20434 |
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, ... |
101-206 |
5.33e-09 |
|
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, previously known as bifunctional carbohydrate esterase (CE)), which is active on complex natural xylans and was identified as the basis of a monophyletic clade gathering all homologs identified in PULs (polysaccharide utilization loci) predicted to act on xylan. It adopts an alpha-beta-hydrolase fold with the catalytic triad Ser-Asp-His. This new family of proteins is a new candidate for biomass processing due to its capacity to remove ferulic acid and acetic acid from natural corn and birchwood xylan substrates.
Pssm-ID: 466583 [Multi-domain] Cd Length: 215 Bit Score: 56.42 E-value: 5.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 101 LNIYTPAdlTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENV-----VVVTIQYRLgiwgffsTGDEHSRgnwghlD 175
Cdd:pfam20434 1 LDIYLPK--NAKGPYPVVIWIHGGGWNSGDKEADMGFMTNTVKALlkagyAVASINYRL-------STDAKFP------A 65
|
90 100 110
....*....|....*....|....*....|....*
2DR0_B 176 QV----AALRWVQDNIASFGGNPGSVTIFGESAGG 206
Cdd:pfam20434 66 QIqdvkAAIRFLRANAAKYGIDTNKIALMGFSAGG 100
|
|
| PRK10162 |
PRK10162 |
acetyl esterase; |
117-205 |
1.10e-04 |
|
acetyl esterase;
Pssm-ID: 236660 [Multi-domain] Cd Length: 318 Bit Score: 44.32 E-value: 1.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 117 VMVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSrgnwghldqVAALRWVQDNIASFGGNP 194
Cdd:PRK10162 83 TLFYLHGGGFILGNLDTHDRIMrlLASYSGCTVIGIDYTLSPEARFPQAIEEI---------VAVCCYFHQHAEDYGINM 153
|
90
....*....|.
2DR0_B 195 GSVTIFGESAG 205
Cdd:PRK10162 154 SRIGFAGDSAG 164
|
|
| LpqC |
COG3509 |
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ... |
103-206 |
3.42e-04 |
|
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];
Pssm-ID: 442732 [Multi-domain] Cd Length: 284 Bit Score: 42.68 E-value: 3.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 103 IYTPADLTKKNRLPVMVWIHGGGlmvGAASTYD---GL-ALAAHENVVVV----TIQYRLGIWGFFSTGDEHSRGnwGHL 174
Cdd:COG3509 41 LYVPAGYDGGAPLPLVVALHGCG---GSAADFAagtGLnALADREGFIVVypegTGRAPGRCWNWFDGRDQRRGR--DDV 115
|
90 100 110
....*....|....*....|....*....|..
2DR0_B 175 DQVAALrwVQDNIASFGGNPGSVTIFGESAGG 206
Cdd:COG3509 116 AFIAAL--VDDLAARYGIDPKRVYVTGLSAGG 145
|
|
| Esterase |
pfam00756 |
Putative esterase; This family contains Esterase D. However it is not clear if all members of ... |
101-235 |
5.68e-04 |
|
Putative esterase; This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.
Pssm-ID: 395613 [Multi-domain] Cd Length: 246 Bit Score: 41.68 E-value: 5.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 101 LNIYTPADLTKKNRLPVMVWIHGGGL--MVGAASTYDGLALAAH-ENVVVVTIQY-----RLGIWGFfstGDEHSRGNWG 172
Cdd:pfam00756 10 VQVYLPEDYPPGRKYPVLYLLDGTGWfqNGPAKEGLDRLAASGEiPPVIIVGSPRggevsFYSDWDR---GLNATEGPGA 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
2DR0_B 173 H--LDQVAA--LRWVQDNiasFGGNPGSVTIFGESAGGesVSVLVLSPLAKNLFHRAISESGVALTS 235
Cdd:pfam00756 87 YayETFLTQelPPLLDAN---FPTAPDGRALAGQSMGG--LGALYLALKYPDLFGSVSSFSPILNPS 148
|
|
| COG4099 |
COG4099 |
Predicted peptidase [General function prediction only]; |
75-206 |
8.29e-04 |
|
Predicted peptidase [General function prediction only];
Pssm-ID: 443275 [Multi-domain] Cd Length: 235 Bit Score: 41.11 E-value: 8.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 75 AGQLLSELFTNRKENIPLKlsedclYlNIYTPADLTKKNRLPVMVWIHGGG---------LMVGAAStYDGLALAAHENV 145
Cdd:COG4099 16 QDGFEARTFTDPSDGDTLP------Y-RLYLPKGYDPGKKYPLVLFLHGAGergtdnekqLTHGAPK-FINPENQAKFPA 87
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
2DR0_B 146 VVVTIQYRLGIWgffstgdehsrgnWGHLDQVAAL-RWVQDNIASFGGNPGSVTIFGESAGG 206
Cdd:COG4099 88 IVLAPQCPEDDY-------------WSDTKALDAVlALLDDLIAEYRIDPDRIYLTGLSMGG 136
|
|
| Fes |
COG2382 |
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism]; |
101-230 |
1.37e-03 |
|
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
Pssm-ID: 441948 [Multi-domain] Cd Length: 314 Bit Score: 40.99 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2DR0_B 101 LNIYTPADLTKKN-RLPVMVWIHGGGL-------MVGAASTYDGLAlAAHE--NVVVVTIQYRLGiwgffSTGDEHSRGN 170
Cdd:COG2382 97 VWVYLPPGYDNPGkKYPVLYLLDGGGGdeqdwfdQGRLPTILDNLI-AAGKipPMIVVMPDGGDG-----GDRGTEGPGN 170
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
2DR0_B 171 WGHLDQVAA--LRWVQDNiASFGGNPGSVTIFGESAGG-ESVSVLVLSPlakNLFHRAISESG 230
Cdd:COG2382 171 DAFERFLAEelIPFVEKN-YRVSADPEHRAIAGLSMGGlAALYAALRHP---DLFGYVGSFSG 229
|
|
| |
