|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
2-284 |
1.48e-167 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 465.16 E-value: 1.48e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 2 IVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKI 81
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTTYPQDENLVELLLLIDALRDEGAKSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 82 TLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLA 161
Cdd:PRK00934 81 TLVIPYLGYARQDKRFKPGEPISARAIAKIISAYYDRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKLDDPLVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 162 PDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241
Cdd:PRK00934 161 PDKGALELAKEAAEILGCEYDYLEKTRISPTEVEIAPKNLDVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKVYVACV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|...
1U9Y_D 242 HPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 284
Cdd:PRK00934 241 HPVLVGDAILKLYNAGVDEIIVTDTLESEVSKISVAPLIADLL 283
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
1-284 |
1.53e-126 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 362.37 E-value: 1.53e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII--NTQKNQNDAIVETILLCDALRDEGV 78
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqqSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 79 KKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDK-LND 156
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAgADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKiLDN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 157 PIVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPT-EIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKK 235
Cdd:TIGR01251 161 PVVVSPDAGGVERAKKVADALGCPLAIIDKRRISATnEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKR 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
1U9Y_D 236 IIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSE-----VSKVSVAEVIVDLL 284
Cdd:TIGR01251 241 VIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEkhkpkVSVISVAPLIAEAI 294
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-280 |
3.95e-97 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 287.73 E-value: 3.95e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII-NTQKNQNDAIVETILLCDALRDEGVK 79
Cdd:COG0462 4 LKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIqSTSPPVNDNLMELLIMIDALKRASAR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 80 KITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDK-LNDP 157
Cdd:COG0462 84 RITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAgADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKdLEDL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 158 IVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKII 237
Cdd:COG0462 164 VVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGAKSVY 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
1U9Y_D 238 AACVHPVLIGDALNKLYSAGVEEVVGTDT-YLSEVSK------VSVAEVI 280
Cdd:COG0462 244 AAATHGVLSGPAVERLENSPIDELVVTDTiPLPEEKRcdkikvLSVAPLL 293
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
1-110 |
1.19e-31 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 113.67 E-value: 1.19e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIIN-TQKNQNDAIVETILLCDALRDEGVK 79
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQsTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|.
1U9Y_D 80 KITLVAPYLAYARQDKKFNPGEAISIRALAK 110
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVAD 111
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
142-266 |
2.52e-23 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 92.46 E-value: 2.52e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 142 AVPKLAEYVKDKLNDP-IVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTL------DAKDRDVFIVDDI 214
Cdd:cd06223 1 AGRLLAEEIREDLLEPdVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSEPYGLelplggDVKGKRVLLVDDV 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
1U9Y_D 215 ISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDAlnKLYSAGVEEVVGTDT 266
Cdd:cd06223 81 IATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| HPT_Archaea |
NF040646 |
hypoxanthine/guanine phosphoribosyltransferase; |
201-234 |
2.87e-03 |
|
hypoxanthine/guanine phosphoribosyltransferase;
Pssm-ID: 468613 Cd Length: 184 Bit Score: 37.98 E-value: 2.87e-03
10 20 30
....*....|....*....|....*....|....
1U9Y_D 201 LDAKDRdVFIVDDIISTGGTMATAVKLLKEQGAK 234
Cdd:NF040646 111 INKGDR-VLIVDDVISTGGTLIAVIKALEKAGAE 143
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
2-284 |
1.48e-167 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 465.16 E-value: 1.48e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 2 IVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKI 81
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTTYPQDENLVELLLLIDALRDEGAKSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 82 TLVAPYLAYARQDKKFNPGEAISIRALAKIYSNIVDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLA 161
Cdd:PRK00934 81 TLVIPYLGYARQDKRFKPGEPISARAIAKIISAYYDRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKLDDPLVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 162 PDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241
Cdd:PRK00934 161 PDKGALELAKEAAEILGCEYDYLEKTRISPTEVEIAPKNLDVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKVYVACV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|...
1U9Y_D 242 HPVLIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 284
Cdd:PRK00934 241 HPVLVGDAILKLYNAGVDEIIVTDTLESEVSKISVAPLIADLL 283
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
1-284 |
1.53e-126 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 362.37 E-value: 1.53e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII--NTQKNQNDAIVETILLCDALRDEGV 78
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqqSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 79 KKITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDK-LND 156
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFKSREPISAKLVANLLETAgADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKiLDN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 157 PIVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPT-EIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKK 235
Cdd:TIGR01251 161 PVVVSPDAGGVERAKKVADALGCPLAIIDKRRISATnEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILKSAGAKR 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
1U9Y_D 236 IIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSE-----VSKVSVAEVIVDLL 284
Cdd:TIGR01251 241 VIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEkhkpkVSVISVAPLIAEAI 294
|
|
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
1-280 |
3.95e-97 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 287.73 E-value: 3.95e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII-NTQKNQNDAIVETILLCDALRDEGVK 79
Cdd:COG0462 4 LKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIqSTSPPVNDNLMELLIMIDALKRASAR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 80 KITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDK-LNDP 157
Cdd:COG0462 84 RITAVIPYYGYARQDRKFRPREPITAKLVADLLEAAgADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSKdLEDL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 158 IVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKII 237
Cdd:COG0462 164 VVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEALKEAGAKSVY 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
1U9Y_D 238 AACVHPVLIGDALNKLYSAGVEEVVGTDT-YLSEVSK------VSVAEVI 280
Cdd:COG0462 244 AAATHGVLSGPAVERLENSPIDELVVTDTiPLPEEKRcdkikvLSVAPLL 293
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
9-284 |
6.34e-72 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 223.28 E-value: 6.34e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 9 SQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQNDAIVETILLCDALRDEGVKKITLVAPYL 88
Cdd:PRK07199 11 NEAAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRPDEKLLPLLFAAEAARELGARRVGLVAPYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 89 AYARQDKKFNPGEAISIRALAKIYSNIVDKLITINP--HETH-IKDFFTIPFIYGDAVPKLAEYVKDKLNDPIVLAPDKG 165
Cdd:PRK07199 91 AYMRQDIAFHPGEAISQRHFARLLSGSFDRLVTVDPhlHRYPsLSEVYPIPAVVLSAAPAIAAWIRAHVPRPLLIGPDEE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 166 ALEFAKTASKILNAEYDYLEKTRLSPTEIQIA-PKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPV 244
Cdd:PRK07199 171 SEQWVAAVAERAGAPHAVLRKTRHGDRDVEISlPDAAPWAGRTPVLVDDIVSTGRTLIEAARQLRAAGAASPDCVVVHAL 250
|
250 260 270 280
....*....|....*....|....*....|....*....|
1U9Y_D 245 LIGDALNKLYSAGVEEVVGTDTYLSEVSKVSVAEVIVDLL 284
Cdd:PRK07199 251 FAGDAYSALAAAGIARVVSTDTVPHPSNAISLAPLLAEAL 290
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
1-280 |
5.62e-59 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 190.33 E-value: 5.62e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEI-NDDEAVIINTQKNQNDAIVETILLCDALRDEGVK 79
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVrGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 80 KITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPF--IYGdaVPKLAEYVKDK-LN 155
Cdd:PRK01259 81 RITAVIPYFGYARQDRKARSRVPITAKLVANLLETAgADRVLTMDLHADQIQGFFDIPVdnLYG--SPILLEDIKQKnLE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 156 DPIVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKK 235
Cdd:PRK01259 159 NLVVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKS 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
1U9Y_D 236 IIAACVHPVLIGDALNKLYSAGVEEVVGTDT-YLSEVSK-------VSVAEVI 280
Cdd:PRK01259 239 VYAYATHPVLSGGAIERIENSVIDELVVTDSiPLSEEAKkcdkirvLSVAPLL 291
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
12-266 |
1.20e-50 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 168.59 E-value: 1.20e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 12 LAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIINTQKNQ-NDAIVETILLCDALRDEGVKKITLVAPYLAY 90
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPiNKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 91 ARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKLNDP--IVLAPDKGAL 167
Cdd:PRK03092 81 ARQDKKHRGREPISARLVADLFKTAgADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDLDnvTVVSPDAGRV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 168 EFA-KTASKILNAEYDYLEKTR--LSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPV 244
Cdd:PRK03092 161 RVAeQWADRLGGAPLAFIHKTRdpTVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIAATHGV 240
|
250 260
....*....|....*....|..
1U9Y_D 245 LIGDALNKLYSAGVEEVVGTDT 266
Cdd:PRK03092 241 LSGPAAERLKNCGAREVVVTDT 262
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
12-280 |
1.35e-44 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 152.93 E-value: 1.35e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 12 LAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIIN-TQKNQNDAIVETILLCDALRDEGVKKITLVAPYLAY 90
Cdd:PLN02369 3 LSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQpTCPPANENLMELLIMIDACRRASAKRITAVIPYFGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 91 ARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPF--IYGDAVpkLAEYVKDKL---NDPIVLAPDK 164
Cdd:PLN02369 83 ARADRKTQGRESIAAKLVANLITEAgADRVLACDLHSGQSMGYFDIPVdhVYGQPV--ILDYLASKTissPDLVVVSPDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 165 GALEFAKT-ASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHP 243
Cdd:PLN02369 161 GGVARARAfAKKLSDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYACATHA 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....
1U9Y_D 244 VLIGDALNKLYSAGVEEVVGTDT-------YLSEVSKVSVAEVI 280
Cdd:PLN02369 241 VFSPPAIERLSSGLFQEVIVTNTipvseknYFPQLTVLSVANLL 284
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
7-282 |
1.42e-41 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 145.71 E-value: 1.42e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 7 SQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII-NTQKNQNDAIVETILLCDALRDEGVKKITLVA 85
Cdd:PRK02269 12 SSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILqSTSSPVNDNLMEILIMVDALKRASAESINVVM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 86 PYLAYARQDKKFNPGEAISiralAKIYSNI-----VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKL---NDP 157
Cdd:PRK02269 92 PYYGYARQDRKARSREPIT----SKLVANMlevagVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGlvgDDV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 158 IVLAPDKGALEFAKTASKILNAEYDYLEKTRlsPTEIQIAPKTL----DAKDRDVFIVDDIISTGGTMATAVKLLKEQGA 233
Cdd:PRK02269 168 VVVSPDHGGVTRARKLAQFLKTPIAIIDKRR--SVDKMNTSEVMniigNVKGKKCILIDDMIDTAGTICHAADALAEAGA 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
1U9Y_D 234 KKIIAACVHPVLIGDALNKLYSAGVEEVVGTDT-YLSE------VSKVSVAEVIVD 282
Cdd:PRK02269 246 TEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTiYLPEerlidkIEQISIADLLGE 301
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
3-266 |
3.04e-41 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 144.88 E-value: 3.04e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 3 VVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEIND-DEAVIINTQKNQNDAIVETILLCDALRDEGVKKI 81
Cdd:PRK02812 24 LFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGcDVYLIQPTCAPVNDHLMELLIMVDACRRASARQI 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 82 TLVAPYLAYARQDKKFNPGEAISiralAKIYSNI-----VDKLITINPHETHIKDFFTIPF--IYGDavPKLAEYVKDK- 153
Cdd:PRK02812 104 TAVIPYYGYARADRKTAGRESIT----AKLVANLitkagADRVLAMDLHSAQIQGYFDIPCdhVYGS--PVLLDYLASKn 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 154 LNDPIVLAPDKGALEFAKTASKILN-AEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQG 232
Cdd:PRK02812 178 LEDIVVVSPDVGGVARARAFAKKLNdAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKEG 257
|
250 260 270
....*....|....*....|....*....|....
1U9Y_D 233 AKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDT 266
Cdd:PRK02812 258 AKQVYACATHAVFSPPAIERLSSGLFEEVIVTNT 291
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
2-282 |
3.87e-41 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 147.33 E-value: 3.87e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 2 IVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIIN-TQKNQNDAIVETILLCDALRDEGVKK 80
Cdd:PTZ00145 121 ILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQpTCPPVNENLIELLLMISTCRRASAKK 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 81 ITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFtipfiyGDAVP---------KLAEYV 150
Cdd:PTZ00145 201 ITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMgVDRVVAIDLHSGQIQGFF------GPRVPvdnleaqliGLDYFT 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 151 KDKLNDPIVLAPDKGALEFAKTASKILNAE------YDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATA 224
Cdd:PTZ00145 275 KKDLYKPVIVSPDAGGVYRARKFQDGLNHRgisdcgIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEA 354
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
1U9Y_D 225 VKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLS--------EVSKVSVAEVIVD 282
Cdd:PTZ00145 355 AKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSnknidsckKITKLSVSVLVAD 420
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
1-282 |
8.81e-39 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 138.14 E-value: 8.81e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIIN-TQKNQNDAIVETILLCDALRDEGVK 79
Cdd:PRK04923 7 LLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQpTCAPSAENLMELLVLIDALKRASAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 80 KITLVAPYLAYARQDKKFNPGEA-ISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYV--KDKLN 155
Cdd:PRK04923 87 SVTAVIPYFGYSRQDRRMRSSRVpITAKVAAKMISAMgADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIwrAYGTD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 156 DPIVLAPDKGALEFAKTASKIL-NAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGAK 234
Cdd:PRK04923 167 NLIVVSPDVGGVVRARAVAKRLdDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAAALKQRGAL 246
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
1U9Y_D 235 KIIAACVHPVLIGDALNKLYSAGVEEVVGTDTY-LSE-------VSKVSVAEVIVD 282
Cdd:PRK04923 247 KVVAYITHPVLSGPAVDNINNSQLDELVVTDTIpLSEaaracakIRQLSVAELLAE 302
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
1-110 |
1.19e-31 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 113.67 E-value: 1.19e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 1 MIVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVIIN-TQKNQNDAIVETILLCDALRDEGVK 79
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQsTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110
....*....|....*....|....*....|.
1U9Y_D 80 KITLVAPYLAYARQDKKFNPGEAISIRALAK 110
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDKPREPITAKLVAD 111
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
2-256 |
4.33e-30 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 115.40 E-value: 4.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 2 IVVSGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII-NTQKNQNDAIVETILLCDALRDEGVKK 80
Cdd:PRK00553 11 VIFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFqSTCSPVNDSLMELLIAIDALKRGSAKS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 81 ITLVAPYLAYARQDKKFNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDFFTIPfiygdaVPKLAEY--------VK 151
Cdd:PRK00553 91 ITAILPYYGYARQDRKTAGREPITSKLVADLLTKAgVTRVTLTDIHSDQTQGFFDIP------VDILRTYhvflsrvlEL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 152 DKLNDPIVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQ 231
Cdd:PRK00553 165 LGKKDLVVVSPDYGGVKRARLIAESLELPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQ 244
|
250 260
....*....|....*....|....*
1U9Y_D 232 GAKKIIAACVHPVLIGDALNKLYSA 256
Cdd:PRK00553 245 KAKKVCVMATHGLFNKNAIQLFDEA 269
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
5-282 |
1.24e-26 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 105.98 E-value: 1.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 5 SGSQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAVII-NTQKNQNDAIVETILLCDALRDEGVKKITL 83
Cdd:PRK02458 14 SLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIqSTSFPVNDHLWELLIMIDACKRASANTVNV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 84 VAPYLAYARQDKKFNPGEAISiralAKIYSNI-----VDKLITINPHETHIKDFFTIPFIYGDAVPKLAEYVKDKL---N 155
Cdd:PRK02458 94 VLPYFGYARQDRIAKPREPIT----AKLVANMlvkagVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGlsgS 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 156 DPIVLAPDKGALEFAKTASKILNA-----EYDYLEKTRLSPTEIQiapktlDAKDRDVFIVDDIISTGGTMATAVKLLKE 230
Cdd:PRK02458 170 DVVVVSPKNSGIKRARSLAEYLDApiaiiDYAQDDSEREEGYIIG------DVAGKKAILIDDILNTGKTFAEAAKIVER 243
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
1U9Y_D 231 QGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSE------VSKVSVAEVIVD 282
Cdd:PRK02458 244 EGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSVATKervpknVTYLSASELIAD 301
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
142-266 |
2.52e-23 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 92.46 E-value: 2.52e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 142 AVPKLAEYVKDKLNDP-IVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQIAPKTL------DAKDRDVFIVDDI 214
Cdd:cd06223 1 AGRLLAEEIREDLLEPdVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSEPYGLelplggDVKGKRVLLVDDV 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
1U9Y_D 215 ISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDAlnKLYSAGVEEVVGTDT 266
Cdd:cd06223 81 IATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
77-270 |
1.33e-19 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 87.31 E-value: 1.33e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 77 GVKKITLVAPYLAYARQDKKfNPGEAISIRALAKIYSNI-VDKLITINPHETHIKDffTIPFIYGDAVPKLAEYVK---- 151
Cdd:PRK06827 121 KARRITVIMPFLYESRQHKR-KGRESLDCALALQELEELgVDNIITFDAHDPRIEN--AIPLMGFENLYPSYQIIKallk 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 152 -------DKlNDPIVLAPDKGALEFAKTASKILNAEYDYLEKTRLSPTEIQ-----IAPKTL--DAKDRDVFIVDDIIST 217
Cdd:PRK06827 198 nekdleiDK-DHLMVISPDTGAMDRAKYYASVLGVDLGLFYKRRDYSRVVNgrnpiVAHEFLgrDVEGKDVLIVDDMIAS 276
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
1U9Y_D 218 GGTMATAVKLLKEQGAKKIIAACVHPvLIGDALNKL---YSAGV-EEVVGTD-TYLSE 270
Cdd:PRK06827 277 GGSMIDAAKELKSRGAKKIIVAATFG-FFTNGLEKFdkaYEEGYfDRIIGTNlVYHPE 333
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
155-242 |
4.40e-13 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 65.46 E-value: 4.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 155 NDPIVLAPDKGALEFAKTASKILNAEYDYLEKTRLSP---TEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQ 231
Cdd:pfam00156 29 KPDVVVGILRGGLPFAGILARRLDVPLAFVRKVSYNPdtsEVMKTSSALPDLKGKTVLIVDDILDTGGTLLKVLELLKNV 108
|
90
....*....|.
1U9Y_D 232 GAKKIIAACVH 242
Cdd:pfam00156 109 GPKEVKIAVLI 119
|
|
| ComFC |
COG1040 |
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General ... |
166-241 |
6.29e-10 |
|
DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain [General function prediction only];
Pssm-ID: 440662 [Multi-domain] Cd Length: 196 Bit Score: 57.52 E-value: 6.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 166 ALEFAKTASKILNAEY--DYLEKTRlsPTEIQiapKTLDAKDR-----DVF--------------IVDDIISTGGTMATA 224
Cdd:COG1040 100 AELLARALARALGIPVlpDLLRRVR--ATPSQ---AGLSRAERrrnlrGAFavrpparlagkhvlLVDDVLTTGATLAEA 174
|
90
....*....|....*..
1U9Y_D 225 VKLLKEQGAKKIIAACV 241
Cdd:COG1040 175 ARALKAAGAARVDVLVL 191
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
7-244 |
5.11e-09 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 56.24 E-value: 5.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 7 SQSQNLAFKVAKL-LNTKLTRVEYKRFPDN--EIYVRIVDEINDdEAVIINTQKNQNDAIVETILLCDALRDEGVKKITL 83
Cdd:PLN02297 23 EETEELARKIAAEsDAIELGSINWRKFPDGfpNLFINNAHGIRG-QHVAFLASFSSPAVIFEQLSVIYALPKLFVASFTL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 84 VAPYLAYARQDKKFNPGEAISIRALAKIYSNIvdKLITINPHETHIKDFFTIP--FIYGDAVPKLAE----YVKDKLN-- 155
Cdd:PLN02297 102 VLPFFPTGTSERVEREGDVATAFTLARILSNI--PISRGGPTSLVIFDIHALQerFYFGDNVLPCFEsgipLLKKRLQql 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 156 ---DPIVLA-PDKGAlefAKTASKILNaeyDYLE----KTRLSPTEIqIAPKTLDAKDRDVFIVDDIISTGGTMATAVKL 227
Cdd:PLN02297 180 pdsDNIVIAfPDDGA---WKRFHKQFE---HFPMvvctKVREGDKRI-VRIKEGNPAGRHVVIVDDLVQSGGTLIECQKV 252
|
250
....*....|....*..
1U9Y_D 228 LKEQGAKKIIAACVHPV 244
Cdd:PLN02297 253 LAAHGAAKVSAYVTHGV 269
|
|
| upp |
PRK00129 |
uracil phosphoribosyltransferase; Reviewed |
202-241 |
3.27e-08 |
|
uracil phosphoribosyltransferase; Reviewed
Pssm-ID: 234653 Cd Length: 209 Bit Score: 52.78 E-value: 3.27e-08
10 20 30 40
....*....|....*....|....*....|....*....|
1U9Y_D 202 DAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241
Cdd:PRK00129 121 DIDERTVIVVDPMLATGGSAIAAIDLLKKRGAKNIKVLCL 160
|
|
| HptA |
COG0634 |
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; ... |
145-242 |
2.11e-07 |
|
Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]; Hypoxanthine-guanine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 440399 Cd Length: 176 Bit Score: 49.64 E-value: 2.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 145 KLAEYVKDKlnDPIVLAPDKGALEF-AKTASKI-LNAEYDYL------EKTRLSPTEIQIAPKTLDAKDRDVFIVDDIIS 216
Cdd:COG0634 25 QITADYAGK--EPLVVGVLKGAFVFmADLLRALdFPLEIDFMhvssygGGTESSGEVRILKDLDEDIEGRDVLIVEDIID 102
|
90 100
....*....|....*....|....*..
1U9Y_D 217 TGGTMATAVKLLKEQGAKKI-IAACVH 242
Cdd:COG0634 103 TGLTLSYLLELLKSRGPASVkIATLLD 129
|
|
| Apt |
COG0503 |
Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein [Nucleotide ... |
153-241 |
2.99e-07 |
|
Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein [Nucleotide transport and metabolism]; Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 440269 Cd Length: 171 Bit Score: 49.30 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 153 KLNDPIVLAPDKGalefaKTASKILNAEYDyLEKTrlSPTEIQIAPKTLDAKDRdVFIVDDIISTGGTMATAVKLLKEQG 232
Cdd:COG0503 69 ALGVPFVPARKPG-----KLPGETVSEEYD-LEYG--TGDTLELHKDALKPGDR-VLIVDDLLATGGTAKAAIKLVEEAG 139
|
....*....
1U9Y_D 233 AkKIIAACV 241
Cdd:COG0503 140 A-EVVGIAF 147
|
|
| PRK09162 |
PRK09162 |
hypoxanthine-guanine phosphoribosyltransferase; Provisional |
142-246 |
7.62e-07 |
|
hypoxanthine-guanine phosphoribosyltransferase; Provisional
Pssm-ID: 181675 Cd Length: 181 Bit Score: 48.32 E-value: 7.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 142 AVPKLAEYVKDKLND--PIVLAPDKGALEFAktaSKILNA-----EYDYLEKTR----LSPTEIQ--IAPKTlDAKDRDV 208
Cdd:PRK09162 25 AIDRMADEITADLADenPLVLCVMGGGLVFT---GQLLPRldfplEFDYLHATRyrneTTGGELVwkVKPRE-SLKGRTV 100
|
90 100 110
....*....|....*....|....*....|....*...
1U9Y_D 209 FIVDDIISTGGTMATAVKLLKEQGAKKIIAAcvhpVLI 246
Cdd:PRK09162 101 LVVDDILDEGHTLAAIRDRCLEMGAAEVYSA----VLV 134
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
202-273 |
8.15e-07 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 48.27 E-value: 8.15e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
1U9Y_D 202 DAKDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACVHPVLIGDALNKLYSAGVEEVVGTDTYLSEVSK 273
Cdd:pfam14572 80 DVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQK 151
|
|
| PRK02304 |
PRK02304 |
adenine phosphoribosyltransferase; Provisional |
208-241 |
1.45e-06 |
|
adenine phosphoribosyltransferase; Provisional
Pssm-ID: 235028 Cd Length: 175 Bit Score: 47.38 E-value: 1.45e-06
10 20 30
....*....|....*....|....*....|....
1U9Y_D 208 VFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241
Cdd:PRK02304 117 VLIVDDLLATGGTLEAAIKLLERLGAEVVGAAFV 150
|
|
| PRK02277 |
PRK02277 |
orotate phosphoribosyltransferase-like protein; Provisional |
204-263 |
1.34e-05 |
|
orotate phosphoribosyltransferase-like protein; Provisional
Pssm-ID: 235023 [Multi-domain] Cd Length: 200 Bit Score: 44.86 E-value: 1.34e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 204 KDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIiaACVhpVLIgdalNKLysaGVEEVVG 263
Cdd:PRK02277 139 EGKRCVIVDDVITSGTTMKETIEYLKEHGGKPV--AVV--VLI----DKS---GIDEIDG 187
|
|
| PLN02293 |
PLN02293 |
adenine phosphoribosyltransferase |
202-241 |
3.27e-05 |
|
adenine phosphoribosyltransferase
Pssm-ID: 177930 Cd Length: 187 Bit Score: 43.51 E-value: 3.27e-05
10 20 30 40
....*....|....*....|....*....|....*....|
1U9Y_D 202 DAKDRdVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241
Cdd:PLN02293 123 EPGER-ALVIDDLIATGGTLCAAINLLERAGAEVVECACV 161
|
|
| PLN02541 |
PLN02541 |
uracil phosphoribosyltransferase |
155-268 |
4.94e-05 |
|
uracil phosphoribosyltransferase
Pssm-ID: 215297 Cd Length: 244 Bit Score: 43.62 E-value: 4.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 155 NDPIVLAPD-KGALEFAKTASKILNAEYDYL------EKTRLSPTEIQIAPKTLDAKDRdVFIVDDIISTGGTMATAVKL 227
Cdd:PLN02541 101 REPVAVVPIlRAGLVLLEHASSVLPATKTYHlgfvrdEETLQPSMYLNKLPDKFPEGSR-VLVVDPMLATGGTIVAAIDE 179
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
1U9Y_D 228 LKEQGAK----KIIAACVHPvligDALNKL---------YSAGVEEVVGTDTYL 268
Cdd:PLN02541 180 LVSRGASveqiRVVCAVAAP----PALKKLsekfpglhvYAGIIDEEVNEKGYI 229
|
|
| UPRTase |
pfam14681 |
Uracil phosphoribosyltransferase; This family includes the enzyme uracil ... |
198-241 |
1.23e-04 |
|
Uracil phosphoribosyltransferase; This family includes the enzyme uracil phosphoribosyltransferase (EC:2.4.2.9). This enzyme catalyzes the first step of UMP biosynthesis.
Pssm-ID: 434124 Cd Length: 204 Bit Score: 42.10 E-value: 1.23e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
1U9Y_D 198 PKTLDakDRDVFIVDDIISTGGTMATAVKLLKEQGA--KKIIAACV 241
Cdd:pfam14681 113 PKDIS--DRTVILLDPMLATGGSAIAAIQVLREHGVpeENIVVLSV 156
|
|
| PLN02238 |
PLN02238 |
hypoxanthine phosphoribosyltransferase |
192-233 |
1.67e-04 |
|
hypoxanthine phosphoribosyltransferase
Pssm-ID: 215132 Cd Length: 189 Bit Score: 41.56 E-value: 1.67e-04
10 20 30 40
....*....|....*....|....*....|....*....|..
1U9Y_D 192 TEIQIAPKTLDAKDRDVFIVDDIISTGGTMATAVKLLKEQGA 233
Cdd:PLN02238 84 AKVSGADLKIDVKGKHVLLVEDIVDTGNTLSALVAHLEAKGA 125
|
|
| apt |
TIGR01090 |
adenine phosphoribosyltransferase; A phylogenetic analysis suggested omitting the ... |
137-239 |
4.60e-04 |
|
adenine phosphoribosyltransferase; A phylogenetic analysis suggested omitting the bi-directional best hit homologs from the spirochetes from the seed for this model and making only tentative predictions of adenine phosphoribosyltransferase function for this lineage. The trusted cutoff score is made high for this reason. Most proteins scoring between the trusted and noise cutoffs are likely to act as adenine phosphotransferase. [Purines, pyrimidines, nucleosides, and nucleotides, Salvage of nucleosides and nucleotides]
Pssm-ID: 273437 Cd Length: 169 Bit Score: 39.95 E-value: 4.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 137 FIYGdavPKLAEyvkdKLNDPIVLAPDKGALEFaktasKILNAEYDyLEktrLSPTEIQIAPKTLDAKDRdVFIVDDIIS 216
Cdd:TIGR01090 58 FIFG---AALAY----KLGVGFVPVRKPGKLPG-----ETISASYD-LE---YGKDVLEIHKDAIKPGQR-VLIVDDLLA 120
|
90 100
....*....|....*....|...
1U9Y_D 217 TGGTMATAVKLLKEQGAKKIIAA 239
Cdd:TIGR01090 121 TGGTAAATDELIKKLGGEVVEAA 143
|
|
| PRK11595 |
PRK11595 |
DNA utilization protein GntX; Provisional |
170-241 |
6.23e-04 |
|
DNA utilization protein GntX; Provisional
Pssm-ID: 183221 [Multi-domain] Cd Length: 227 Bit Score: 40.41 E-value: 6.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 170 AKTASKILNAEYDYLEKTRLSPTEIQiapKTLDA-----------------KDRDVFIVDDIISTGGTMATAVKLLKEQG 232
Cdd:PRK11595 138 CRPLARWLGCDYDSEALTRTRATATQ---HFLSArlrkrnlknafrlelpvQGQHMAIVDDVVTTGSTVAEIAQLLLRNG 214
|
....*....
1U9Y_D 233 AKKIIAACV 241
Cdd:PRK11595 215 AASVQVWCL 223
|
|
| PTZ00149 |
PTZ00149 |
hypoxanthine phosphoribosyltransferase; Provisional |
204-241 |
7.49e-04 |
|
hypoxanthine phosphoribosyltransferase; Provisional
Pssm-ID: 240293 Cd Length: 241 Bit Score: 40.14 E-value: 7.49e-04
10 20 30
....*....|....*....|....*....|....*...
1U9Y_D 204 KDRDVFIVDDIISTGGTMATAVKLLKEQGAKKIIAACV 241
Cdd:PTZ00149 149 KDKHVLIVEDIIDTGNTLVKFCEYLKKFEPKTIRIATL 186
|
|
| PRK07322 |
PRK07322 |
adenine phosphoribosyltransferase; Provisional |
201-253 |
1.20e-03 |
|
adenine phosphoribosyltransferase; Provisional
Pssm-ID: 180928 Cd Length: 178 Bit Score: 38.81 E-value: 1.20e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
1U9Y_D 201 LDAKDRD------VFIVDDIISTGGTMATAVKLLKEQGAKkiIAACVHPVLIGDALNKL 253
Cdd:PRK07322 110 LDGADAEklkgkrVAIVDDVVSTGGTLTALERLVERAGGQ--VVAKAAIFAEGDASNRL 166
|
|
| pyrE |
PRK00455 |
orotate phosphoribosyltransferase; Validated |
208-234 |
1.80e-03 |
|
orotate phosphoribosyltransferase; Validated
Pssm-ID: 234771 Cd Length: 202 Bit Score: 38.60 E-value: 1.80e-03
10 20
....*....|....*....|....*..
1U9Y_D 208 VFIVDDIISTGGTMATAVKLLKEQGAK 234
Cdd:PRK00455 116 VLVVEDVITTGGSVLEAVEAIRAAGAE 142
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
208-234 |
2.02e-03 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 38.60 E-value: 2.02e-03
10 20
....*....|....*....|....*..
1U9Y_D 208 VFIVDDIISTGGTMATAVKLLKEQGAK 234
Cdd:COG0461 115 VLVVEDVITTGGSVLEAVEALREAGAE 141
|
|
| HPT_Archaea |
NF040646 |
hypoxanthine/guanine phosphoribosyltransferase; |
201-234 |
2.87e-03 |
|
hypoxanthine/guanine phosphoribosyltransferase;
Pssm-ID: 468613 Cd Length: 184 Bit Score: 37.98 E-value: 2.87e-03
10 20 30
....*....|....*....|....*....|....
1U9Y_D 201 LDAKDRdVFIVDDIISTGGTMATAVKLLKEQGAK 234
Cdd:NF040646 111 INKGDR-VLIVDDVISTGGTLIAVIKALEKAGAE 143
|
|
| PLN02440 |
PLN02440 |
amidophosphoribosyltransferase |
98-265 |
3.17e-03 |
|
amidophosphoribosyltransferase
Pssm-ID: 215241 [Multi-domain] Cd Length: 479 Bit Score: 38.89 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 98 NPGEAISIRAlakiysnivDKLIT---INPHET-------HIkdFFTIP--FIYGDAV--------PKLAEYVKDKLnDP 157
Cdd:PLN02440 211 NPGEVIVVDK---------DKGVSsqcLMPHPEpkpcifeHI--YFARPnsIVFGRSVyesrlefgEILATEIPVDC-DV 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1U9Y_D 158 IVLAPDKG---ALEFAKtaskILNAEYD-------YLEKTRLSPTE--------IQIAPKTLDAKDRDVFIVDDIISTGG 219
Cdd:PLN02440 279 VIPVPDSGrvaALGYAA----KLGVPFQqglirshYVGRTFIEPSQkirdfsvkLKLNPVRSVLEGKRVVVVDDSIVRGT 354
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
1U9Y_D 220 TMATAVKLLKEQGAKK---------IIAACVHPV-------LIGdalNKLYSAGVEEVVGTD 265
Cdd:PLN02440 355 TSSKIVRMLREAGAKEvhmriasppIIASCYYGVdtpsreeLIS---NRMSVEEIRKFIGCD 413
|
|
| |
