7UTE,3QZZ,1OR4


Conserved Protein Domain Family
Protoglobin

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pfam11563: Protoglobin (491947 is an unknown moldel)
Protoglobin
This family includes protoglobin from Methanosarcina acetivorans C2A. It is also found near the N-terminus of the Haem-based aerotactic transducer HemAT in Bacillus subtilis. It is part of the haemoglobin superfamily. Protoglobin has specific loops and an amino-terminal extension which leads to the burying of the haem within the matrix of the protein. Protoglobin-specific apolar tunnels allow the access of O2, CO and NO to the haem distal site. In HemAT it acts as an oxygen sensor domain.
Statistics
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PSSM-Id: 491947
Aligned: 63 rows
Threshold Bit Score: 78.0297
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7UTE_B        20 TDLEFDLLKKTVMLGEKDVMYLKKAGDVLKDQVDEILDLLVGWRASNEHLIYYFSNpdtgepiKEYLERVRARFGAWILD 99  Aeropyrum pernix
WP_014823232  31 SMPELAQQMNLIGLAEENLRHIKSYQPAIAAGVSEITDVFYENVLAVPSLKKIIEE-------RTKIDRLKKTLSSYIIS 103 Solibacillus si...
Q5WC98        26 DESDCQKQIGFIDLHASDLEYIHLLYPLVNEHIAPITEAFYEKLLEQPHLRQLVTT-------HSSIDALKQTLKQHILE 98  Bacillus clausi...
Q9KFH4        32 AESELSAQLRMIHLTLDDLKRMKALQPLVEENMEVLADAFYSNIIKQPNLNEIIET-------HSSVERLKETLKQHILE 104 Bacillus halodu...
WP_015893065  35 GKSTLAKQLAMINLTEEELSIVKALQPLIIQNIEAIIDYFYASIENEPLLMKIVDQ-------NSTIERLKLTLKRHICE 107 Brevibacillus
WP_013487448  24 KGTEMERQLKMINLTEKDLEVINAIQPFISKRINVIVDRFYKNLEIESSLLDIIND-------NSSIDRLKVTLKQHITE 96  Evansella cellu...
WP_009793853  31 lsEEVLRQIDMIGLQDSDLNYILSLQPYVKGNLPAIIEQFYKNLENEKTLTKIIND-------NSSVERLKNTLSAHIYE 103 Bacillus
1OR4_A        30 kHADVKKQLKMVRLGDAELYVLEQLQPLIQENIVNIVDAFYKNLDHESSLMDIIND-------HSSVDRLKQTLKRHIQE 102 Bacillus subtilis
Q65LP1        29 QHAEFKKQLAMVDLTDEDLWVLSRLKPLVTEHIETIVTRFYQNLEHESSLMEIIHD-------NSSVDRLKKTLTIHIQE 101 Bacillus lichen...
WP_014822396  32 TYPNLHKQIELLKLTKEDLAVIKQLEPFAQQVVPDMVEKFYGAISLSPELVDIIGS-------SARMDRLKGTLTKHLEA 104 Solibacillus si...
7UTE_B       100 TTSRDYNREWLDYQYEVGLRHHrskkgvtdgvrtVPHIPLRYLIAQIYPLTATIKPFLAKKGGSPEDIEGMYNAWFKSVV 179 Aeropyrum pernix
WP_014823232 104 MFDGVFNEETIEAKRKLARMHF------------KIGLDPKWYMGTFQKLQETMIMLISKDIADVAGREIIQLNVSKLIN 171 Solibacillus si...
Q5WC98        99 MFEGKVDAAFFAKRKRIAQTHV------------RIGLKTKWYIGAFHNLQLELQRMIVKHFKSGNEQFLAFCAVGKFIN 166 Bacillus clausi...
Q9KFH4       105 MFNGEIDQAFLQKRLQIAQAHV------------RIGLQTKWYVSAFQQLTDSLIQLLEQHLQSPSDIVLATRSLLKLLN 172 Bacillus halodu...
WP_015893065 108 MFSGRIDSAYIEQRSRIAVIHM------------RIGLEPKWYLSAFQNMLVSLIDLLQKNIADKDEFVQAITAVTKILS 175 Brevibacillus
WP_013487448  97 MFDGLIDEQYYSKRVRIAHIHV------------KIGLQTKWYMSAFQDLLLSLMELVDEIIEDKTECLYIIKAITKVIN 164 Evansella cellu...
WP_009793853 104 MFSGKIDTEFIQQRSVIAHVHV------------KIGLQPKWYMCAFQDLYLSLCSMIIDTISEKGPCTGAMLAVSKIIS 171 Bacillus
1OR4_A       103 MFAGVIDDEFIEKRNRIASIHL------------RIGLLPKWYMGAFQELLLSMIDIYEASITNQQELLKAIKATTKILN 170 Bacillus subtilis
Q65LP1       102 MFSGVIDEAFLEKRIRIAHVHL------------RIGLLPKWYLGAFQDLLLSMLKIFENAL-SDEEYRRSVKAVTKILN 168 Bacillus lichen...
WP_014822396 105 MFNCNINSHYIEERQTIAHVHV------------KIGLQSKWYIASFQSLMTTFIDFISKIEMSNVDMAKAVDAFSKLIN 172 Solibacillus si...
7UTE_B       180 LQVAIWSHPYTKendW 195 Aeropyrum pernix
WP_014823232 172 LEMQVVLEEYEKenlN 187 Solibacillus silvestris
Q5WC98       167 FEQQLVLEAYEEeerR 182 Bacillus clausii KSM-K16
Q9KFH4       173 LEQQLVLEAYENenkR 188 Bacillus halodurans
WP_015893065 176 IEQQIVLEEYENeheK 191 Brevibacillus
WP_013487448 165 LEQQLVLEAYEIetkR 180 Evansella cellulosilytica
WP_009793853 172 LEQQIVLEAYEQeisr 187 Bacillus
1OR4_A       171 LEQQLVLE-------- 178 Bacillus subtilis
Q65LP1       169 IEQQIVLEAFEDehar 184 Bacillus licheniformis DSM 13 = ATCC 14580
WP_014822396 173 FEQQLVIEAYEKeeqR 188 Solibacillus silvestris
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