Conserved Protein Domain Family
DUF1776

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pfam08643: DUF1776 
Fungal family of unknown function (DUF1776)
This is a fungal family of unknown function. One of the proteins in this family Swiss:P32792 has been localized to the mitochondria.
Statistics
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PSSM-Id: 370028
Aligned: 13 rows
Threshold Bit Score: 260.052
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q7SGR1       121 GRMDVVVIAGSANLPLTRSVALDLERKGFIVFIVSSGPEDDIAIQNLA-RPD-IRPLGVDtt------dPLSASASIERF 192 Neurospora crassa
EDK45246     123 ARRDAVLLIGSPTEPLTRAIALDMERRGFIVFLTMLDSTDSKYVLSHPfNEE-IQMVDFF---------TKSVEDSLVEF 192
Q6BYC2       121 ARGDVVLIVGSPTEPLTRLIALDFEKRGFVVYLTILDEKDFKYIESNQiTED-INYLNLNe--------SYSFEVQISKF 191 Debaryomyces ha...
ABN67526     127 ARRDIVLVVGSPTEPLTRLIALDFEKRGFIVYLTILDEKDFKYVESNPiTDD-INYLNLNd--------TLSYESQLSKF 197
Q757L8       117 GERETVLVLGEMTDPITRALVYDLHRRGFCVFVCSTSEKRDRQLEDE--YEK-VPSPWDQeggvchmaaTPEAVARLTEF 193 Eremothecium go...
Q6FY03        26 TENQCILVFGDMRDPIIRGQVMDLYRRGFTLFVCLENAGTYKTHNDEDdFLNyIDPKSTSd------------WAKFSEF 93  [Candida] glabrata
P32792       106 AESQVVLILGDMNDPIIRNQVMDLYRRRFTVYICTENADVYKKHEEDQdFIYyIDPTCEKd---------------FEGF 170 Saccharomyces c...
Q6CXG9       116 DDNQVLLVLGDIRDPVVRNQVNELYRRRFIVFVCKRKLK-YGTGEPEDdFT--IDDLTSDdggifyidaDSSGLASFIQY 192 Kluyveromyces l...
Q9URV8        91 QKTQVVVL--SAWNPLASVIAHDLDRRGFIVVVLVRDASEAATVSLQQ-RPY-IQSLIVTh------------NEAVERF 154 Schizosaccharom...
Q2HDB5       121 GRMDVVVIAGSPALPLTRSLSLDLERKGFVVFVVANSHEDEIMIQHLA-RPD-IRPLSIDit------dPPSTGTSIDTF 192 Chaetomium glob...
XP_001265378 122 ARKEIVVVAGSPHEPMTRAIATDLERRGYIVFITVTSAQEEQLVRSED-RMD-IRALWLDlta---tpsPSEIHPSLRDI 196
Q5BGM7       120 ARKEIIAVAGSPHEPMTRSIAADLDRRGYIVYITVSSAEEEHLVRAEN-RPD-IRPLWLDlttl--pssPSEIHSSLNEI 195 Aspergillus nid...
Q6C017       132 ARTEVVVLAGSFLEPIVRVVANDLDKRGFIVYVTTTSEAETALIEKEN-SAD-IRSLSVNtq------kADVIKSTMKEF 203 Yarrowia lipoly...
Q7SGR1       193 ATYLQSPHAAVPNSKRHRLHLKAVILIPSLNY-QTSPIATIPPSGFANlFNTHLLHPI-ITLQAFLPLLTArlgptpsae 270 Neurospora crassa
EDK45246     193 KQTLKTPIVPFHGAKPHVLQLKSVIFTPSLYF-SVGPVENLGINTWQK-LQDRMMMFFkMFSCGLIQLMRM--------- 261
Q6BYC2       192 RQLLEIPVVPFPGADSHYLRLTSVIFAPSLYF-PIGPIENITVASWNK-MNERFSTYLkLFSSGLVNLIRS--------- 260 Debaryomyces ha...
ABN67526     198 QQLLELPVIPFPGAEPHNLRLVGVVFAPSLFF-PIGPIENITVATWTK-FTDRELLYLkLFSSGLISLIRN--------- 266
Q757L8       194 LQREER-------------RLRGVLVVPSSCFfTSGMFTNIPEGQVRSeLQENLVNTW-AVVTRLLPQFDSas------- 252 Eremothecium go...
Q6FY03        94 FRKFPTN------------TLSAILLIPKLSYhPTG---QVTLEQLENeLHSNVLIYY-STLVAISPHLPQns------- 150 [Candida] glabrata
P32792       171 FVDVP--------------RLASILFMPRLSYhPSG---VISCDSLESeIHSSIFVYY-QALLSIIPHLK---------- 222 Saccharomyces c...
Q6CXG9       193 MNDHSEK------------QLRSILFMPNLSYyPSG--NTLSSKLVTNeVQENILNYY-GVLEKLIPHFAGna------- 250 Kluyveromyces l...
Q9URV8       155 LLSFSNQ----SGPKEYALRLRGLILVPTGDS-LYTPIENIGKDAWISaFQ-QLSESF-SNVSRMIPLLKS--------- 218 Schizosaccharom...
Q2HDB5       193 ARYLQSTHAAIPNGKRHHLLLKAVILIPSLNY-QTSPIATIPPSSFADlFNTHLLQPI-LTIQAFLPLLTArlspp---- 266 Chaetomium glob...
XP_001265378 197 HSLITQPQWPMPGVPPHTCQLSGTILVPSPNY-TTGPVATIPPSAWADtINTRLLSPI-LTTQIFLPLLTLr-------- 266
Q5BGM7       196 HSLITQPHAPMAGVPPHVCQLSGLILVPSPKF-VAGPVATIPPSSWVDtINTRLLSPI-LTTQLFLPLLTLr-------- 265 Aspergillus nid...
Q6C017       204 GTFLATPQVAFPNAKPHVLRLAGVVLVPDLYY-PFGPIEQMHLESWNSvINSKLLAPLaLLSQGLLTLVRQtas------ 276 Yarrowia lipoly...
Q7SGR1       271 ssssgsdkkkDSPKIIVCTPSIISSINPPFHAPEATVCSALSAFTEVLTAELR---PLAIPVTHIQLGTFDFAGftpasa 347 Neurospora crassa
EDK45246     262 ----------QKARLILVNLNNLNSLNLPYHAPESIFQNELKLLFTILTREMK---SHEIYVTQVRLGNINLSNq----- 323
Q6BYC2       261 ----------QQSKIILINANIISCLDMPYHAPETIFLNSVRHLFTALSRELS---QHNISVTQIRLGNLNISNq----- 322 Debaryomyces ha...
ABN67526     267 ----------QQSKTILISTNIVSSLEIPYHAPETLFQNHLKHLFTTLTREVR---QHGLSVTQVRLGNLHLSNq----- 328
Q757L8       253 ---------rDKLQVVVFNPSLSQKLNLQYHSLELLMSSTMESLYRILANECG----YLADVYQCHLGILNIA------- 312 Eremothecium go...
Q6FY03       151 --------nsNRIPTLIYNPSLSVNMKNVEHPVEWLISGLMTTIFEELKHSHI------FDPYMINVGLFQLG------- 209 [Candida] glabrata
P32792       223 ----------RKTQLIMFNPSLTADLNLVHHSTEIITSGIIDSLFKIFKEYQR------LNVSTIKLGILQIG------- 279 Saccharomyces c...
Q6CXG9       251 ---------fKKLQLIFFNPSLSKNLQLKHHSVEHLVSGLISTFYETMKIEYS----HQCDVYMCHIGILGIG------- 310 Kluyveromyces l...
Q9URV8       219 ----------QKARIIGLSHGILSAYEPPNYAVPSILSSSIETFLRTLKRETG------LQVICIKLGNLSFLNy----- 277 Schizosaccharom...
Q2HDB5       267 -----sdkerPSPKVLVFTPSIISSINPPFHAPEATICSALSAFTEVLTGELR---PLGIPVTHMQLGTFDFAGftp--- 335 Chaetomium glob...
XP_001265378 267 ---------nTNSTILVLYPSISSSLSAPFAGPEVTTARALSGFATSLRTELRllqHKNIDVVELKLGNIDL-------- 329
Q5BGM7       266 ---------nTNSTIILVYPSISSSLSAPFAGPEVATARALSGFATSLRRELSllqHHNIDLVELKLGNIDL-------- 328 Aspergillus nid...
Q6C017       277 --------tpNPARLVIVTPNITAALSPAYSAPEAMVVSGINALATSLDRELA---PHGIKTTHIRLGSFDVSH------ 339 Yarrowia lipoly...
Q7SGR1       348 arehwqerNSQGVPLRALEANPQdaesLLPWPDSARHAYGKNFVTQSSSAISTGRIrg-mRGSSLRELHNAVFDVIDGSI 426 Neurospora crassa
EDK45246     324 --------KVGSNSRIESIVQSE----VRSWTSEMKNLYADNFARAQYKSHKIRGCg--gQGSSIRELFHLLFDLTYESS 389
Q6BYC2       323 --------DGASESKIATIVNSE----IRSWNEDIKELYASNFSSSQYKANPIKSTg---RGTSLRQLYHLMFDLIYAKG 387 Debaryomyces ha...
ABN67526     329 --------RSNSGSRIANLVNSE----IRSWDEDMRSLYADSFSKAQYKANPIKSTg--gRGTSLRELYHILFDLLYSKG 394
Q757L8       313 --------GNASNYKYLTINGSH----------ITKALCEPIYELLLS------------RDNMWVRFKRWL-------- 354 Eremothecium go...
Q6FY03       210 --------GQLSNYKYLNVKGSN----------IYNDLYWPIYCFIKMK-----------GGNTFQKLHVAICSLFG--- 257 [Candida] glabrata
P32792       280 --------SQPSNYKFLRMAGSD----------IHEALHYPVYKMIMSA-----------NGYKLRQLLSWLTTLGG--- 327 Saccharomyces c...
Q6CXG9       311 --------GNASTFKYLSVKGSN----------ISKSLCEPIYQLILS------------RDYMWLRLKRWL-------- 352 Kluyveromyces l...
Q9URV8       278 --------DHSSSPGKSNYPPSL---------------------------------------CTERKVLNKIFDSLLGCW 310 Schizosaccharom...
Q2HDB5       336 ------aaNSRLLQPHGLLTAPEda-eALPWPDSARHAYGKNFVSQSGSAIGAGRIrg-mRGSSLKELHNAVFDVIDGSL 407 Chaetomium glob...
XP_001265378 330 --------GPQFRDAQSHVTGTE----VLAWSAQQRSLYGPQYLSSIEQRPVASAGpstvRGSPARTLHYAVLDALEPAS 397
Q5BGM7       329 --------GPQYRAPNSHIAGTE----VLTWSVQQRALYGPQYLNSIEQKPVASAGpgyiRGSPARALHNALLDALEPTS 396 Aspergillus nid...
Q6C017       340 --------GHSQSKQLASAIHAD----LITWSEDMRAAYS-NYGGTMAFLYGCRST----RGSSLKRLNFAIYDSLTVRR 402 Yarrowia lipoly...
Q7SGR1       427 ---------TKGTVRVGLGASVYGF-----VGRWVPRGLVA 453 Neurospora crassa
EDK45246     390 ---------VPAIAYCGKGARFYDR-----VAKILPESWVS 416
Q6BYC2       388 k--------NPPVVYCGTGARIYDW-----VSKIIPESILA 415 Debaryomyces hansenii
ABN67526     395 r--------SPGIVYCGTGARAYAI-----ISKLLPESWLE 422
Q757L8       355 ---------QGPVLYCGKGSRLACW-----LRSYAPLWLLE 381 Eremothecium gossypii
Q6FY03       258 ---------LKRTFYLGKFSYLFTLpftskLYKLLNEWYVL 289 [Candida] glabrata
P32792       328 ---------YNSVYYCGRFSYLVSWpfaslIFNHHTRLSLK 359 Saccharomyces cerevisiae S288C
Q6CXG9       353 ---------SGSILYCGKGSALTSW-----LGYLCPLWLLD 379 Kluyveromyces lactis
Q9URV8       311 ---------PSPTRHVGCRTFFMVT-----VSRFLPTCVID 337 Schizosaccharomyces pombe 972h-
Q2HDB5       408 ---------TNGTVQVGLGANIYGF-----VGRWVPKGLVS 434 Chaetomium globosum CBS 148.51
XP_001265378 398 kdifgrkvpKKRVIYAGRGARSYSI-----IGEWVPAGLVG 433
Q5BGM7       397 knifgqrtaKKPVRYAGRGARTYHW-----IGQWTPPGLVG 432 Aspergillus nidulans
Q6C017       403 ---------PKRVWHVGFGSRMYEL-----VAAFLPECVLS 429 Yarrowia lipolytica
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