1TVE


Conserved Protein Domain Family
NAD_binding_3

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pfam03447: NAD_binding_3 
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Homoserine dehydrogenase, NAD binding domain
This domain adopts a Rossmann NAD binding fold. The C-terminal domain of homoserine dehydrogenase contributes a single helix to this structural domain, which is not included in the Pfam model.
Statistics
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PSSM-Id: 281446
Aligned: 21 rows
Threshold Bit Score: 67.3303
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1TVE_A  11 GAGVVGSAFLDQLLAMKSt------iTYNLVLLAEAErsLISKDfsplnvgsdwKAALAASTTKTLPLDDLIAhlk--ts 82   baker's yeast
Q8TZ45  10 GAGGIGTTVLREIREGRLe------gKVEPVLVCDRHp-EKLKR----------IERWFPDCDTSTDLDDAMS------- 65   Methanopyrus kandler...
P08499  25 GFGTVGTEVMRLMTEYGDelahriggPLEVRGIAVSD---ISKP----------RE-GVAPELLTEDAFALIEr------ 84   Corynebacterium glut...
P46806  14 GLGNVGSEVVRIIEGSADdlaarigaPLMLRGIGVRR---VAVD----------R--GVPVDLLTDNIEELVSr------ 72   Mycobacterium leprae TN
P19582  10 GLGTVGSGVVKIIQDHQDklmhqvgcPVTIKKVLVKD---LEKK----------REVDLPKEVLTTEVYDVIDd------ 70   Bacillus subtilis su...
P52986   9 GLGTVGSGTVEILQDPQGrsp--llkAIEVKAVGVRS---LDKP----------RQVNLPPEVLTTDLEAIVTd------ 67   Synechocystis sp. PC...
P49079 568 GPGLIGRTLLNQLKDQAAvlkenmniDLRVMGIAGSRtmLLSDIgvd----ltqWKEKLQTEAEPANLDKFVHhlsenhf 643  Zea mays
P00562 465 GKGNIGSRWLELFAREQStlsartgfEFVLAGVVDSRrsLLSYDgld----asrALAFFNDEAVEQDEESLFLwmra-hp 539  Escherichia coli K-12
P44505 472 GVGGVGGELIEQVKRQKEylak-knvEIRVCAIANSNrmLLDENgln----ledWKNDLENATQPSDFDVLLSfikl-hh 545  Haemophilus influenz...
P00561 472 GVGGVGGALLEQLKRQQSwlkn-khiDLRVCGVANSKalLTNVHgln----lenWQEELAQAKEPFNLGRLIRlvke-yh 545  Escherichia coli K-12
1TVE_A  83 pK-PVILVDN-TSSAYIAGFYTKFVENGISIATPNKKAFSsDLATWKALFSNKPTNGF-VYHE 142  baker's yeast
Q8TZ45  66 -AeADVLLEA-ASVEAAASLLPDALKR-FDVIVMSVGALVlEEGLLSRCREVAEVTGHrLHVP 125  Methanopyrus kandleri AV19
P08499  85 eD-VDIVVEViGGIEYPREVVLAALKAGKSVVTANKALVA---AHSAELADAAEAANVdLYFE 143  Corynebacterium glutamicum ATCC 13032
P46806  73 aD-VDIVVEVmGPVELSRKAILSALEHGKSVVTANKALLA---ASTGELAQAAESAHVdLYFE 131  Mycobacterium leprae TN
P19582  71 pD-VDVVIEViGGVEQTKQYLVDALRSKKHVVTANKDLMA---VYGSELLAEAKENGCdIYFE 129  Bacillus subtilis subsp. subtilis str...
P52986  68 pD-IAIVVELmGGLEPARSLILQAIAHKKHIVTANKAVIA---RYGPEIYEAANQHGVyVLLE 126  Synechocystis sp. PCC 6803 substr. Ka...
P49079 644 fP-NRVLVDC-TADTSVASHYYDWLKKGIHVITPNKKANSgPLDRYLKLRTLQRASYThYFYE 704  Zea mays
P00562 540 yD-DLVVLDV-TASQQLADQYLDFASHGFHVISANKLAGAsDSNKYRQIHDAFEKTGRhWLYN 600  Escherichia coli K-12
P44505 546 vV-NPVFVDC-TSAESVAGLYARALKEGFHVVTPNKKANTrELVYYNELRQNAQASQHkFLYE 606  Haemophilus influenzae Rd KW20
P00561 546 lL-NPVIVDC-TSSQAVADQYADFLREGFHVVTPNKKANTsSMDYYHQLRYAAEKSRRkFLYD 606  Escherichia coli K-12
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