2M46


Conserved Protein Domain Family
arsC_related

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TIGR01617: arsC_related 
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transcriptional regulator, Spx/MgsR family
This model represents a portion of the proteins within the larger set covered by pfam03960. That larger family includes a glutaredoxin-dependent arsenate reductase (TIGR00014). Characterized members of this family include Spx and MgsR from Bacillus subtili. Spx is a global regulator for response to thiol-specific oxidative stress. It interacts with RNA polymerase. MgsR (modulator of the general stress response, also called YqgZ) provides a second level of regulation for more than a third of the proteins in the B. subtilis general stress regulon controlled by Sigma-B. [Regulatory functions, DNA interactions]
Statistics
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PSSM-Id: 273720
Aligned: 6 rows
Threshold Bit Score: 147.962
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2M46_A    26 IKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDl-KNkLQTLSDDE 104 Staphylococcus aure...
AAK64292   2 IKLYTSGSSKSSREARAWLEANGLPFQEISLSKQGISKEQILELLARSEDGVDSLVSRRSKAFQALD--ID-FDALSLKQ 78  Lactobacillus rhamn...
P54503     5 LTFYSYPSCTSCRKTKHWLKAHQIEFNERHLFRETPTREELKYILSLTTEGIDEILATRSQTFKNLN--LN-IEEMTVNE 81  Bacillus subtilis s...
CAC92294  10 LRLYGIKNCDTIKKARRWLEEQGIAYQFHDYRADGLSDECLQGFIDTLG--WEPLLNTRGTTWRKLPp-EQrDAITDAQS 86  Yersinia pestis CO92
BAB77719   3 IQVYGIPNCGTCKKTFNWLQAHKVDYEFINTKENPPTREHIQNWVKSLS--STPMRNTSGQSYRALG---EeKKNWTDEQ 77  Nostoc sp. PCC 7120
Q9PQW7     2 IYVLYSPNCAVCKKVVRFFRNNQIEITKIIIGEDKIERSMLLDILSLCEDGFGTIISFKTESSKRLNitSKtFLDLSTKE 81  Ureaplasma parvum s...
2M46_A   105 KLELLSSDGMLVKRPLAVMGDk----IT-LGFKEDQYKETWL 141 Staphylococcus aureus subsp. aureus COL
AAK64292  79 AVDLLAEKPAILRRPIIVDER-----RLlFGFNQDSVRVFLP 115 Lactobacillus rhamnosus
P54503    82 VLELLIEKPKLLRRPILVDNK-----KLvIGYNPGELLKLSK 118 Bacillus subtilis subsp. subtilis str. 168
CAC92294  87 AKALMLAQPAIIKRPLLEGPNg----EMlLGFKIESYQEFIH 124 Yersinia pestis CO92
BAB77719  78 WIEEFAKDAMLLKRPLFVKDGi----AVaVGFRDEKIIREKL 115 Nostoc sp. PCC 7120
Q9PQW7    82 LLNLIQNDLNLIRRPLIYQTKnnrpyRLqIGYDSEEIEIFKR 123 Ureaplasma parvum serovar 3 str. ATCC 700970
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