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Report for CCDS6191.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
6191.2 Public Homo sapiens 8 VXN 24 110 108 CCDS HistoryNCBI Gene:254778Re-query CCDS DB by CCDS ID:6191.2Re-query CCDS DB by GeneID:254778See the combined annotation on chromosome 8 in Sequence Viewer

Public Note for CCDS 6191.1
The coding region has been updated to extend the N-terminus to one that is more supported by available transcript and primate conservation data. Two possible start codons are present in this update, with the downstream start codon having a stronger Kozak signal. Due to leaky scanning by ribosomes, it is possible that some ribosomes may initiate translation from the upstream AUG codon while others start from the downstream AUG. Translation initiation from the downstream AUG would result in a protein that is 1 aa shorter at the N-terminus.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 6191.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000305454.8 ENSP00000302260.3 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000305454.8Link to Ensembl Protein Viewer:ENSP00000302260.3Re-query CCDS DB by Nucleotide ID:ENST00000305454Re-query CCDS DB by Protein ID:ENSP00000302260
Original member Current member EBI ENST00000699189.1 ENSP00000514189.1 Accepted alive Link to Ensembl Transcript Viewer:ENST00000699189.1Link to Ensembl Protein Viewer:ENSP00000514189.1Re-query CCDS DB by Nucleotide ID:ENST00000699189Re-query CCDS DB by Protein ID:ENSP00000514189
Original member Current member NCBI NM_152765.4 NP_689978.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_152765.4Link to Protein Sequence:NP_689978.2Re-query CCDS DB by Nucleotide ID:NM_152765Re-query CCDS DB by Protein ID:NP_689978Link to BLAST:NP_689978.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_689978.2 207 Q8TAG6-1 207 100% 0 0

Chromosomal Locations for CCDS 6191.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 8 (NC_000008.11)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8See the combined annotation on chromosome 8 in Sequence Viewer

Chromosome Start Stop Links
8 66493649 66493718 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 66496437 66496492 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 66505375 66505528 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 66510096 66510157 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 66513540 66513637 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8
8 66515893 66516076 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 8Link to Ensembl Genome Browser on chromosome 8

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (624 nt):
ATGATGCATCAGATTTACAGCTGCAGTGACGAGAACATAGAAGTTTTCACCACCGTGATTCCTTCCAAGG
TATCCAGTCCAGCCAGAAGAAGAGCCAAAAGCTCTCAGCACCTCTTGACCAAGAATGTGGTGATCGAGTC
GGACCTGTACACGCACCAGCCCCTGGAGCTGCTGCCCCACCGCGGAGACCGCAGGGACCCTGGCGACCGC
CGCAGGTTTGGGCGGCTCCAGACCGCGCGGCCGCCCACAGCCCACCCGGCCAAAGCCTCTGCCAGACCCG
TGGGGATTTCTGAACCCAAAACATCAAATCTGTGTGGGAATCGAGCATATGGAAAATCTCTGATACCGCC
AGTGCCCCGGATCTCAGTGAAAACTTCAGCCTCTGCCTCATTGGAGGCGACAGCCATGGGCACAGAGAAG
GGAGCTGTTCTGATGAGAGGATCCAGACATCTCAAGAAGATGACTGAAGAGTATCCAGCCCTTCCCCAAG
GAGCAGAAGCCTCTCTACCACTGACAGGCAGTGCTTCCTGCGGCGTCCCCGGCATCCTCCGGAAAATGTG
GACAAGGCACAAGAAGAAGTCTGAATATGTGGGAGCCACCAACAGCGCCTTTGAGGCCGACTAA

Translation (207 aa):
MMHQIYSCSDENIEVFTTVIPSKVSSPARRRAKSSQHLLTKNVVIESDLYTHQPLELLPHRGDRRDPGDR
RRFGRLQTARPPTAHPAKASARPVGISEPKTSNLCGNRAYGKSLIPPVPRISVKTSASASLEATAMGTEK
GAVLMRGSRHLKKMTEEYPALPQGAEASLPLTGSASCGVPGILRKMWTRHKKKSEYVGATNSAFEAD


Links Key
 Links to:   History report
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 Re-query CCDS DB by:   CCDS ID
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 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
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