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Report for CCDS31539.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
31539.2 Public Homo sapiens 11 LRRC55 24 110 108 CCDS HistoryNCBI Gene:219527Re-query CCDS DB by CCDS ID:31539.2Re-query CCDS DB by GeneID:219527See the combined annotation on chromosome 11 in Sequence Viewer

Public Note for CCDS 31539.1
This CCDS representation uses the 5'-most in-frame start codon, which is conserved in higher primates. Two alternative downstream start codons also exist, each with stronger Kozak signals and the second being most widely conserved. It is possible that leaky scanning by ribosomes would allow either of the downstream start codons to be used, at least some of the time. The use of a downstream start codon would result in a protein that is 25 aa or 30 aa shorter at the N-terminus. There is no experimental evidence showing which start codon is preferentially used in vivo.

Public since: CCDS release 3, NCBI annotation release 36.2, Ensembl annotation release 41

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
CDS uses downstream AUG

Sequence IDs included in CCDS 31539.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000497933.3 ENSP00000419542.2 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000497933.3Link to Ensembl Protein Viewer:ENSP00000419542.2Re-query CCDS DB by Nucleotide ID:ENST00000497933Re-query CCDS DB by Protein ID:ENSP00000419542
Original member Current member NCBI NM_001005210.4 NP_001005210.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_001005210.4Link to Protein Sequence:NP_001005210.2Re-query CCDS DB by Nucleotide ID:NM_001005210Re-query CCDS DB by Protein ID:NP_001005210Link to BLAST:NP_001005210.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_001005210.2 298 Q6ZSA7 298 100% 0 0

Chromosomal Locations for CCDS 31539.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 11 (NC_000011.10)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11See the combined annotation on chromosome 11 in Sequence Viewer

Chromosome Start Stop Links
11 57182023 57182683 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 57187245 57187480 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (897 nt):
ATGGGTGACACTTGGGCCCAGCTTCCCTGGCCCGGGCCACCCCACCCAGCAATGCTGCTGATCTCCCTCC
TCTTGGCAGCCGGGTTGATGCACTCGGATGCCGGCACCAGCTGCCCCGTCCTTTGCACATGCCGTAACCA
GGTGGTGGATTGTAGCAGCCAGCGGCTATTCTCCGTGCCCCCAGACCTGCCAATGGACACCCGAAACCTC
AGCCTGGCCCACAACCGCATCACAGCAGTGCCGCCTGGCTACCTCACATGCTACATGGAGCTCCAGGTGC
TGGATTTGCACAACAACTCCTTAATGGAGCTGCCCCGGGGCCTCTTCCTCCATGCCAAGCGCTTGGCACA
CTTGGACCTGAGCTACAACAATTTCAGCCATGTGCCAGCCGACATGTTCCAGGAGGCCCATGGGCTAGTC
CACATCGACCTGAGCCACAACCCCTGGCTGCGGAGGGTGCATCCCCAGGCCTTTCAGGGCCTCATGCAGC
TCCGAGACCTGGACCTCAGTTATGGGGGCCTGGCCTTCCTCAGCCTGGAGGCTCTTGAGGGCCTACCGGG
GCTGGTGACCCTGCAGATCGGTGGCAATCCCTGGGTGTGTGGCTGCACCATGGAACCCCTGCTGAAGTGG
CTGCGAAACCGGATCCAGCGCTGTACAGCAGATTCTCAGCTGGCTGAGTGCCGGGGCCCTCCTGAAGTCG
AGGGCGCCCCGCTCTTCTCACTCACTGAGGAGAGCTTCAAGGCCTGCCACCTGACCCTGACCCTGGATGA
TTACCTATTCATTGCGTTCGTGGGCTTCGTGGTCTCCATTGCTTCTGTGGCCACCAACTTCCTCCTGGGC
ATCACTGCCAACTGCTGCCACCGCTGGAGCAAGGCCAGTGAAGAGGAAGAGATCTGA

Translation (298 aa):
MGDTWAQLPWPGPPHPAMLLISLLLAAGLMHSDAGTSCPVLCTCRNQVVDCSSQRLFSVPPDLPMDTRNL
SLAHNRITAVPPGYLTCYMELQVLDLHNNSLMELPRGLFLHAKRLAHLDLSYNNFSHVPADMFQEAHGLV
HIDLSHNPWLRRVHPQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKW
LRNRIQRCTADSQLAECRGPPEVEGAPLFSLTEESFKACHLTLTLDDYLFIAFVGFVVSIASVATNFLLG
ITANCCHRWSKASEEEEI


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

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