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Report for CCDS21932.2 (current version)
CCDS |
Status |
Species |
Chrom. |
Gene |
CCDS Release |
NCBI Annotation Release |
Ensembl Annotation Release |
Links |
21932.2 |
Public |
Mus musculus |
7 |
Edrf1 |
23 |
108 |
98 |
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Public Note for CCDS 21932.1 |
The coding region has been updated to extend the N-terminus. The use of an alternative upstream start codon would result in a protein that is 1 aa longer. The uAUG appears to be only conserved in mouse and rat, while the dAUG shows much better conservation. This means that the second AUG, which has a stronger Kozak signal, may also be used due to leaky scanning past the first AUG. |
Public since: CCDS release 2, NCBI annotation release 36.1, Ensembl annotation release 39
Review status: Reviewed (by RefSeq, Havana and CCDS collaboration) Sequence IDs included in CCDS 21932.2
Original |
Current |
Source |
Nucleotide ID |
Protein ID |
Status in CCDS |
Seq. Status |
Links |
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EBI |
ENSMUST00000051169.12 |
ENSMUSP00000059166.6 |
Accepted |
alive |
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NCBI |
NM_178115.4 |
NP_835216.3 |
Updated |
not alive |
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NCBI |
NM_178115.5 |
NP_835216.3 |
Accepted |
alive |
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Chromosomal Locations for CCDS 21932.2
Assembly GRCm38.p6 (GCF_000001635.26)
CCDS Sequence Data |
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Blue highlighting indicates alternating exons. | Red highlighting indicates amino acids encoded across a splice junction. | | Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair. |
Nucleotide Sequence (3723 nt): ATGATGGGGGACCCCAAGGAAGCAGGAGCCGAGGCTTCTCCTTCAGGGGCGGCCGCCCGAGGAGGGCTCA GCCTCCTGTCCCAGGCGGACTCCGAGGAGCCTTCTGCACAGGGATCGGCCTTATTTCTTGGAGGCAACGA AGTGAAAAGCAGAGCTGTGGTAAAATACTCTTCTGCCCCTCCTCGAACAGCGTTTGCACGTCTCGAAGAA AAAACAGACTTGAAACTCCCACCTGCCAACTGGTTACGAGAGAGTGCCAAACTAGGGCCAGCAGGAACCA CCATTCTTGGCAATAGTAAGAAAAGCAAGCCGTTTTCAAGTTTCGGCATGGCGTATGACTTCATTGACTC GGTGGGAAATGATGTGGATGTCGTCTCCGACTCAGAAAACATAAAAAAGCTCCTGAAGATTCCCTACAGC AAGTCCCACGTGAGCATGGCTGTGCACCGCATAGGAAGGACCCTCTTACTAGATGAGCTGGACATTCAAG AACTCTTTATGAGGTCATCTCAGACTGGTGATTGGACATGGTTGAAAGAGTTCTATCAAAGACTGATCGA TCAGAAGTGGCAGAGGAAGAAGAAAAGCAAGGAGCACTGGTATCAGAAGGCTATTCTTTCCAAGTTCTTG TACTACAGCATCAATGGTGATGGAGCTGCGCAGCCTGTCCCGTCTCCTGCAGAACAAGAAGAGTCATCGA GTTCTCAGCAGACACATGAGTCTGAAGGGGCCGCCTGGCCTGCTCCCTTTGAAATGCCCTCTTCCGTGTC TGAGGATCCCAGTGCTTCCAGTCAGGGCAGGGAGCCTCTTGAGCCCTCATGCATAGTGGGGCATGTGGCC TCAGCACCTAAAGAGCAAAACCTTACTACTTTGTTCAATGACGGGGAGAACAGTCAGGGTCTTAAAAATG ATTTCGTCCGGAATATCCTGTGGACTTTTGAAGATATTCATATGCTAGTTGGGTCTAACATGCCTATATT TGGTGGAGGCAGATATCCAGCAGTTAGCTTACGTCTCAGGGATAACAACAAACCGATTAACGTGTTAACT GGAATAGACTATTGGTTGGACAACCTGATATGCAATGTTCCAGAGCTCGTGATGTGCTTCCATGTTAACG GGATCGTACAGAAATATGAAATGATAAAGACAGAAGAAATCCCCAATTTGGAAAACTCTAATTTTTCTAC CAAAGTTATAAAAGACATTGCACAAAATATTTTATCATTTCTTAAATCTAATTGTACCAAAGAAGGGCAT ACCTATTGGCTCTTTAAAGCAAGCGGCAGTGATATTGTGAAACTCTACGACCTCACGACTCTGTGTGAAG AAACTGAAGACAAGTACCAGAACCCATTCACAATGCCAGTGGCTATCCTCTTATACAAGGTTGCTTGTAA CATGATGATGAAGAAAAATCAAAACAAGAAACACTATGGAACTATTAGAACATTGCTTCTCAACTGTGTT AAGTTGTTGGACAAAAGCAGACATCCTCAAATTATTGCTTCAGCCAACTACATGCTTTCAGAGCTTTTCC AGCTGGATGAGCCTAAAAAGGAGGAAAGTTCAGACTCCCCTTTAAATGAGAATTCGGATGAAAGCTACAG TGAAGAGGAGGAGGAGATGGCAGACAGTGATGAGAATGGATCCTACAGCACCAGCTCTGACCCAGCAGAT GACAACAAGGCAGTGGCTATCATTAAGTCTGTTGGAGAACTGTCAGTACCGGAAAAATACAAGTCGATTC ATCAGATCAGACCCAGTTGTGCATTTCCCGTTTGCCATGACACAGAAGAGCGCTGTCGACTCGTCCTTAG CTATGTGTTGGAGGGTTTAAAATCTGTAGATAGTAGCATCAAAAAAGAAAGCGACCTTCCAGCAGCTGAC CCCAGCACTCCTATCCCCTTAAAATATGAAGATGAATCCACAAGGGGTGGCCCTGAGGGGCTGGAGAAGC AGATGGCCTTGTTCCTGGACAAAATGGGCTCCATTCAGAAGGGCAGTTGTTCTGGGCAGTCTGGAATGAC CCCTGGTTCTTGGCAACATAAAATGAAACTTCAGCTGATTCTCAAGTCATCAAAGGCCTACTACATTTTG TCAGATGCTGCCATGAGTCTTCAGAAGTATGGAAGAGCATTGAGATACATTAAGCTAGCTCTACAGAGCC ATGATACTTACTGCTGCCTCTGCACCAACATGCTTTCTGAAGTGCTGCTGTTCCTCTCTCAATACCTGAC ACTTTGCGGCGACATCCAACTCATGCTGGCCCAGAATGCAAATAACCGAGCAGCACACCTCGAGGAGTTT AATTACCAAACAAAAGAAGACCAGGAGATCCTCCACAGTCTCCACAGAGAGTCCAGCTGCCAGGGATTTG CATGGGCAACAGATCTATCTACAGACTTAGAAAGTCAACTCTCAGTTAGTTGTAAATGTTATGAGGCTGC TAATGAAATCTTGCAATTCAGCGACTTAAAAAGTCAGAATCCAGAACACTATGTACAGGTGTTGAAGAGA ATGGGAAACATTAGAAATGAAATCGGTGTATTCTACATGAATCAGGCTGCTGCACTGCAGGGTGAGCGAG TAGTGAGCAAATCTGTGTCTGCTGCAGAGCAACAATTGTGGAAAAAAAGCTTTTCTTGTTTTGAAAAGGG GATTCACAACTTTGAGTCGATTGATGATGCTACAAATGCTGCCCTTCTGCTGTGCAACACGGGAAGACTC ATGCGGGTCTGTGCGCAGGCGCACTGCGGTGCAGAGGATGAGTTCAAACGGGAGTTCTCTCCAGAGGAGG GCTTGTATTACAGCAAGGCCGTTGATTACTATTTGAAGGCTCTGAGGTCATTGGGAACGAGAGACATGCA CCCAATTGTTTGGGATTCTGTGAACTGGGAATTGTCCACTACATACTTCACCATGGCGACTCTGCAGCAA GATTATGCTCCATTATCCAGAAAAGCTCAGGAGCAGATTGAGAAAGAAGTGAGCGAGGCTATGATGAAGT CCCTGAAGCACTGCGATGTTGACTCAGCAACTGCTCGGCAGCCCCTCTGTCAGTACCGAGCTGCGACCAT CCATCACAGGCTGGCTTCCATGTACCACAGCTGTCTGAGGAACCAGGTTGGTGATGAGCATCTTAGGAAG CAGCACCGAGTGCTGGCAGATCTCCACTACAGCAAAGCTGCGAAGCTCTTTCAGCTTCTCAAAGACGCTC CCTGTGAACTGCTTAGAGTGCAGCTAGAAAGGGTGGCATTTGCAGAATTTCAGATGAGCAGTCAGAATAG CAATGTTGGAAAGTTAAAAACATTATCTGGGGCACTTGATATCATGGTGAGAACGGAGCATGCGTTCCAG CTCATCCGGAAGGAGCTTGTAGAGGAATGTGACCAGCCCAAGAATGATGAGGCTACACCGGCTGCTGATT CTTCACCTAATCTTAATCGAGAAGAAGTGATCAAACTCCTTAGTATATTTGAATCTCGTCTGTCATTCCT TCTCCTTCAATCCATCAAACTGATGTCGTCATCTAAAAGGAAAATGAGCAGTAACGCTGAAGAAGACATA GTCCTCCAAACCAACAAGCAGATTTACTCCCAGCTTTTGAGAGCGACTGCCAACAGAAACTCAACTCTGC TGGAAAGAATTGAAGTCGTCATCTGTTTGCTGGAGCAGCTTGCCTCCGGTAGCAGCCGATCGAGTGGCAG TGCTGTCCCCTGA
Translation (1240 aa): MMGDPKEAGAEASPSGAAARGGLSLLSQADSEEPSAQGSALFLGGNEVKSRAVVKYSSAPPRTAFARLEE KTDLKLPPANWLRESAKLGPAGTTILGNSKKSKPFSSFGMAYDFIDSVGNDVDVVSDSENIKKLLKIPYS KSHVSMAVHRIGRTLLLDELDIQELFMRSSQTGDWTWLKEFYQRLIDQKWQRKKKSKEHWYQKAILSKFL YYSINGDGAAQPVPSPAEQEESSSSQQTHESEGAAWPAPFEMPSSVSEDPSASSQGREPLEPSCIVGHVA SAPKEQNLTTLFNDGENSQGLKNDFVRNILWTFEDIHMLVGSNMPIFGGGRYPAVSLRLRDNNKPINVLT GIDYWLDNLICNVPELVMCFHVNGIVQKYEMIKTEEIPNLENSNFSTKVIKDIAQNILSFLKSNCTKEGH TYWLFKASGSDIVKLYDLTTLCEETEDKYQNPFTMPVAILLYKVACNMMMKKNQNKKHYGTIRTLLLNCV KLLDKSRHPQIIASANYMLSELFQLDEPKKEESSDSPLNENSDESYSEEEEEMADSDENGSYSTSSDPAD DNKAVAIIKSVGELSVPEKYKSIHQIRPSCAFPVCHDTEERCRLVLSYVLEGLKSVDSSIKKESDLPAAD PSTPIPLKYEDESTRGGPEGLEKQMALFLDKMGSIQKGSCSGQSGMTPGSWQHKMKLQLILKSSKAYYIL SDAAMSLQKYGRALRYIKLALQSHDTYCCLCTNMLSEVLLFLSQYLTLCGDIQLMLAQNANNRAAHLEEF NYQTKEDQEILHSLHRESSCQGFAWATDLSTDLESQLSVSCKCYEAANEILQFSDLKSQNPEHYVQVLKR MGNIRNEIGVFYMNQAAALQGERVVSKSVSAAEQQLWKKSFSCFEKGIHNFESIDDATNAALLLCNTGRL MRVCAQAHCGAEDEFKREFSPEEGLYYSKAVDYYLKALRSLGTRDMHPIVWDSVNWELSTTYFTMATLQQ DYAPLSRKAQEQIEKEVSEAMMKSLKHCDVDSATARQPLCQYRAATIHHRLASMYHSCLRNQVGDEHLRK QHRVLADLHYSKAAKLFQLLKDAPCELLRVQLERVAFAEFQMSSQNSNVGKLKTLSGALDIMVRTEHAFQ LIRKELVEECDQPKNDEATPAADSSPNLNREEVIKLLSIFESRLSFLLLQSIKLMSSSKRKMSSNAEEDI VLQTNKQIYSQLLRATANRNSTLLERIEVVICLLEQLASGSSRSSGSAVP
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