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Report for CCDS9145.3 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
9145.3 Public Homo sapiens 12 ANAPC7 24 110 108 CCDS HistoryNCBI Gene:51434Re-query CCDS DB by CCDS ID:9145.3Re-query CCDS DB by GeneID:51434See the combined annotation on chromosome 12 in Sequence Viewer

Public Note for CCDS 9145.1
The coding region has been updated to extend the N-terminus to one that is more supported by available conservation data. It should be noted that there is limited transcript evidence extending to the start codon of the update (human DB003237.1 and DA484190.1, macaque CJ446700), which is present in a CpG island. An alternative downstream in-frame start codon codon also exists, with both start codons having weak Kozak signals. Due to leaky scanning by ribosomes, it is possible that some ribosomes may initiate translation from the upstream AUG codon while others start from the downstream AUG. Translation initiation from the downstream AUG would result in a protein that is 34 aa shorter at the N-terminus.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 9145.3

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000455511.9 ENSP00000394394.4 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000455511.9Link to Ensembl Protein Viewer:ENSP00000394394.4Re-query CCDS DB by Nucleotide ID:ENST00000455511Re-query CCDS DB by Protein ID:ENSP00000394394
Original member Current member NCBI NM_016238.3 NP_057322.3 MANE Select Accepted alive Link to Nucleotide Sequence:NM_016238.3Link to Protein Sequence:NP_057322.3Re-query CCDS DB by Nucleotide ID:NM_016238Re-query CCDS DB by Protein ID:NP_057322Link to BLAST:NP_057322.3

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_057322.3 565 Q9UJX3-1 565 100% 0 0

Chromosomal Locations for CCDS 9145.3

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 12 (NC_000012.12)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12See the combined annotation on chromosome 12 in Sequence Viewer

Chromosome Start Stop Links
12 110374144 110374333 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110376066 110376216 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110377393 110377617 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110381752 110381948 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110382843 110382960 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110386327 110386469 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110387739 110387892 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110388512 110388623 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110395101 110395220 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110396266 110396452 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12
12 110403527 110403627 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 12Link to Ensembl Genome Browser on chromosome 12

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1698 nt):
ATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCA
GCTTGTTACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGT
GTATCATGCAGATTCTCTCTTTCATGATAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTA
CAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAACTGGAAATTCTGCATCTACTCCAC
AAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAAACA
AGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAATAAACATGATG
CTGGCAAACCTGTACAAGAAGGCTGGTCAGGAGCGCCCTTCAGTCACCAGCTATAAGGAGGTGCTGAGGC
AGTGCCCATTAGCCCTTGATGCCATTCTAGGCTTGTTGTCCCTTTCTGTAAAAGGGGCAGAGGTGGCATC
CATGACAATGAATGTGATCCAAACCGTGCCTAACTTGGACTGGCTCTCTGTGTGGATCAAAGCGTATGCT
TTTGTGCACACTGGTGACAACTCAAGAGCAATCAGTACCATCTGTTCACTAGAGAAAAAATCCTTATTGC
GAGATAACGTGGACCTATTGGGAAGCTTGGCAGATCTGTACTTCAGAGCTGGAGACAATAAAAACTCTGT
CCTCAAGTTTGAACAGGCACAGATGTTGGATCCTTATCTGATAAAAGGAATGGATGTATATGGCTACCTA
CTGGCACGAGAAGGGCGGCTAGAGGATGTTGAGAACCTTGGATGCCGCCTTTTCAATATCTCTGATCAGC
ATGCAGAACCGTGGGTGGTTTCTGGCTGTCACAGCTTCTATAGCAAACGCTACTCCCGGGCCCTCTATTT
AGGAGCCAAGGCCATTCAGCTGAACAGTAATAGTGTTCAAGCTCTGCTACTTAAGGGAGCAGCACTTAGG
AACATGGGCAGAGTCCAAGAAGCAATAATCCACTTTCGGGAGGCCATACGGCTCGCACCTTGTCGCTTAG
ATTGTTATGAAGGTCTTATCGAATGTTACTTAGCCTCCAACAGTATTCGAGAAGCAATGGTAATGGCTAA
CAACGTTTACAAAACTCTGGGAGCAAATGCACAGACCCTTACCCTTTTAGCCACCGTTTGTCTTGAAGAC
CCAGTGACACAGGAGAAAGCCAAAACATTATTAGATAAAGCCCTGACCCAAAGGCCAGATTACATTAAGG
CTGTGGTGAAAAAAGCAGAACTACTTAGCAGAGAACAGAAATATGAAGATGGAATTGCTTTGCTGAGGAA
CGCACTGGCTAATCAGAGTGACTGTGTCCTGCATCGGATCCTAGGAGATTTCCTTGTAGCTGTCAATGAG
TATCAGGAGGCAATGGACCAGTATAGTATAGCACTAAGTTTGGACCCCAATGACCAGAAGTCTCTAGAGG
GGATGCAGAAGATGGAGAAGGAGGAGAGTCCCACGGATGCCACTCAGGAGGAGGATGTGGACGACATGGA
AGGGAGTGGGGAAGAAGGGGACCTGGAGGGCAGCGACAGTGAGGCGGCCCAGTGGGCTGACCAGGAGCAG
TGGTTCGGCATGCAGTGA

Translation (565 aa):
MNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMAL
QQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMM
LANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYA
FVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYL
LAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALR
NMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLED
PVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNE
YQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQ
WFGMQ


Links Key
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