CCDS Home FTP Process Releases & Statistics
Collaborators EBI HGNC MGI NCBI
Contact Us email CCDS
Genome Displays Related Resources Gene HomoloGene MANE RefSeq
|
|
Report for CCDS7144.2 (current version)
CCDS |
Status |
Species |
Chrom. |
Gene |
CCDS Release |
NCBI Annotation Release |
Ensembl Annotation Release |
Links |
7144.2 |
Public |
Homo sapiens |
10 |
ARHGAP21 |
24 |
110 |
108 |
|
Public Note for CCDS 7144.1 |
The coding region has been updated to extend the N-terminus to one that is more supported by available transcript and conservation data. Two possible start codons are present in this update, with the downstream start codon having a stronger Kozak signal. Due to leaky scanning by ribosomes, it is possible that some ribosomes may initiate translation from the upstream AUG codon while others start from the downstream AUG. Translation initiation from the downstream AUG would result in a protein that is 1 aa shorter at the N-terminus. The shorter protein is described in the literature (PMIDs 12056806, 15793564 and 17347647). |
Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23
Review status: Reviewed (by RefSeq, Havana and CCDS collaboration) Sequence IDs included in CCDS 7144.2
Original |
Current |
Source |
Nucleotide ID |
Protein ID |
MANE |
Status in CCDS |
Seq. Status |
Links |
---|
|
|
EBI |
ENST00000396432.7 |
ENSP00000379709.2 |
MANE Select |
Accepted |
alive |
|
|
|
NCBI |
NM_001367448.1 |
NP_001354377.1 |
|
Accepted |
alive |
|
|
|
NCBI |
NM_001367454.1 |
NP_001354383.1 |
|
Accepted |
alive |
|
|
|
NCBI |
NM_020824.4 |
NP_065875.3 |
MANE Select |
Accepted |
alive |
|
Chromosomal Locations for CCDS 7144.2
Assembly GRCh38.p14 (GCF_000001405.40)
CCDS Sequence Data |
---|
Blue highlighting indicates alternating exons. | Red highlighting indicates amino acids encoded across a splice junction. | | Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair. |
Nucleotide Sequence (5877 nt): ATGATGGCCACGCGTCGGACTGGTCTGTCTGAGGGAGATGGTGACAAGCTCAAGGCCTGCGAGGTCTCAA AAAATAAAGATGGAAAAGAACAAAGTGAAACTGTATCACTGTCTGAAGATGAAACATTCTCCTGGCCAGG TCCCAAAACAGTTACGTTGAAAAGAACATCTCAAGGCTTTGGTTTTACATTAAGACATTTTATTGTTTAT CCCCCAGAGTCTGCAATTCAATTTTCATATAAGGATGAAGAAAATGGAAACAGAGGAGGAAAACAAAGAA ACCGCTTGGAACCAATGGATACCATATTTGTTAAGCAAGTTAAAGAAGGAGGACCTGCTTTTGAAGCTGG ATTATGTACAGGTGACCGAATTATAAAAGTCAATGGAGAAAGTGTTATTGGCAAAACCTATTCCCAAGTA ATTGCTTTAATTCAAAACAGTGATACAACATTGGAACTTAGTGTTATGCCAAAAGATGAAGACATTCTCC AAGTGCTACAGTTTACAAAGGATGTCACAGCACTGGCATATTCTCAAGATGCCTACCTGAAAGGCAACGA AGCTTATAGCGGCAATGCCCGCAATATACCTGAACCTCCACCAATCTGCTATCCCTGGCTGCCATCTGCC CCATCAGCCATGGCACAGCCAGTTGAAATATCTCCTCCTGACTCATCATTGAGCAAACAGCAAACCAGTA CACCAGTACTGACACAACCTGGTAGGGCCTATAGAATGGAAATACAAGTGCCTCCATCACCAACAGATGT TGCAAAATCAAACACAGCAGTGTGTGTTTGCAATGAAAGTGTAAGGACTGTCATTGTGCCTTCTGAGAAG GTTGTAGATTTGTTATCCAATAGAAACAACCATACAGGTCCTTCACATAGAACTGAAGAAGTGAGGTATG GCGTGAGTGAGCAGACCTCTTTAAAAACAGTGTCAAGAACCACATCACCACCATTATCAATTCCCACCAC TCATCTAATTCATCAGCCTGCAGGCTCCAGATCACTGGAACCTTCTGGAATTTTACTTAAGTCTGGAAAT TACAGTGGACATTCTGATGGAATCTCAAGCAGCAGATCTCAAGCTGTGGAGGCTCCCTCTGTATCTGTTA ATCACTATTCGCCAAATTCCCATCAGCACATAGACTGGAAAAACTATAAAACTTACAAAGAGTATATTGA TAACAGACGATTGCACATAGGTTGTCGGACAATACAAGAAAGATTAGATAGTTTAAGAGCAGCATCTCAA AGCACGACAGATTATAACCAGGTCGTCCCCAACCGCACTACTTTGCAGGGACGACGTCGAAGCACCTCTC ATGATCGAGTGCCCCAGTCTGTCCAGATACGGCAACGCAGTGTGTCCCAAGAAAGACTGGAAGATTCTGT GCTAATGAAGTATTGTCCAAGAAGTGCATCTCAAGGAGCACTGACGTCTCCATCTGTTAGTTTTAGTAAT CATAGAACTCGTTCATGGGATTATATTGAGGGACAGGATGAAACCTTAGAAAATGTCAATTCTGGAACTC CAATACCTGATTCCAATGGAGAGAAAAAACAGACTTACAAGTGGAGTGGGTTTACTGAACAGGATGATAG ACGAGGTATTTGTGAAAGACCTAGGCAGCAAGAAATTCATAAATCTTTTCGAGGTTCCAATTTTACTGTG GCTCCAAGCGTTGTTAATTCTGATAACAGGCGAATGAGTGGTAGAGGAGTGGGATCTGTGTCGCAGTTTA AAAAAATTCCACCAGATCTAAAAACATTGCAGTCAAACAGAAATTTTCAGACTACTTGTGGAATGTCACT GCCTCGGGGTATTTCACAAGACAGGTCACCTCTTGTGAAAGTCCGAAGTAATTCTCTGAAAGCTCCTTCC ACGCATGTCACAAAACCATCATTTAGCCAGAAATCATTTGTTTCTATCAAAGACCAAAGACCAGTAAATC ACTTGCATCAGAACAGTCTGTTGAATCAGCAGACATGGGTAAGGACTGACAGTGCCCCCGATCAGCAAGT GGAGACTGGGAAATCCCCCTCTTTATCTGGAGCCTCTGCCAAGCCTGCCCCTCAGTCGAGTGAAAACGCT GGTACTTCAGATTTAGAACTACCTGTCAGTCAAAGGAATCAAGATTTAAGTTTACAAGAGGCTGAAACTG AGCAATCAGATACTTTAGATAATAAAGAAGCTGTCATCCTAAGGGAAAAACCTCCATCTGGACGCCAGAC ACCGCAGCCTTTAAGGCATCAGTCTTACATCTTGGCAGTAAATGACCAGGAGACCGGGTCAGACACTACC TGCTGGCTGCCCAATGATGCACGTCGAGAGGTCCACATAAAAAGAATGGAGGAAAGAAAAGCCTCGAGTA CCAGTCCGCCTGGCGATTCTTTGGCTTCCATCCCATTTATAGATGAACCAACTAGCCCTAGCATTGATCA TGATATTGCACATATCCCTGCCTCTGCTGTTATATCAGCCTCTACCTCTCAGGTCCCCTCCATAGCAACA GTTCCTCCTTGCCTCACAACTTCAGCTCCATTAATTCGCCGTCAGCTCTCACATGACCACGAATCTGTTG GCCCTCCTAGCCTGGATGCTCAGCCCAACTCAAAGACAGAAAGATCAAAATCATATGATGAGGGTCTGGA TGATTACAGAGAAGATGCAAAATTGTCCTTTAAGCACGTATCTAGTCTGAAGGGAATCAAGATCGCAGAC AGCCAAAAGTCATCAGAAGACTCTGGGTCCAGAAAAGATTCTTCCTCAGAGGTCTTCAGTGATGCTGCCA AGGAAGGGTGGCTTCATTTCCGACCCCTTGTCACCGATAAGGGCAAGCGAGTTGGTGGAAGTATTCGGCC ATGGAAACAGATGTATGTTGTCCTTCGGGGTCATTCACTTTACCTGTACAAAGATAAAAGAGAGCAGACG ACTCCGTCTGAGGAAGAGCAGCCCATCAGTGTTAATGCTTGCTTGATAGACATCTCTTACAGTGAGACCA AGAGGAAAAATGTGTTTCGACTCACCACGTCCGACTGTGAATGCCTGTTTCAGGCTGAAGACAGAGATGA TATGCTAGCTTGGATCAAGACGATCCAGGAGAGCAGCAACCTAAACGAAGAGGACACTGGAGTCACTAAC AGGGATCTAATTAGTCGAAGAATAAAAGAATACAACAATCTGATGAGCAAAGCAGAACAGTTGCCAAAAA CACCTCGCCAGAGTCTCAGCATCAGGCAAACTTTGCTTGGTGCTAAATCAGAGCCAAAGACTCAAAGCCC ACACTCTCCGAAGGAAGAGTCGGAAAGGAAACTTCTCAGTAAAGATGATACCAGTCCCCCAAAAGACAAA GGCACATGGAGAAAAGGCATTCCAAGTATCATGAGAAAGACATTTGAGAAAAAGCCAACTGCTACAGGAA CTTTCGGCGTCCGACTAGATGACTGCCCACCAGCTCATACTAATCGGTATATTCCATTAATAGTTGACAT ATGTTGCAAATTAGTTGAAGAAAGAGGTCTTGAATATACAGGTATTTATAGAGTTCCTGGAAATAATGCA GCCATCTCAAGTATGCAAGAAGAACTCAACAAGGGAATGGCTGATATTGATATACAAGATGATAAATGGC GAGATTTGAATGTGATAAGCAGTTTACTAAAATCCTTCTTCAGAAAACTCCCTGAGCCTCTCTTCACAAA TGATAAATATGCTGATTTTATTGAAGCCAATCGTAAAGAAGATCCTCTAGATCGTCTGAAAACATTAAAA AGACTAATTCACGATTTGCCTGAACATCATTATGAAACACTTAAGTTCCTTTCAGCTCATCTGAAGACAG TGGCAGAAAATTCAGAAAAAAATAAGATGGAACCAAGAAACCTAGCAATAGTGTTTGGTCCCACCCTTGT TCGAACATCAGAAGACAACATGACCCACATGGTCACCCACATGCCTGACCAGTACAAGATTGTAGAAACG CTCATCCAGCACCATGACTGGTTTTTCACAGAAGAAGGTGCTGAAGAGCCTCTTACAACAGTGCAGGAGG AAAGCACAGTAGACTCCCAGCCAGTGCCAAACATAGATCATTTACTCACCAACATTGGAAGGACAGGAGT CTCCCCAGGAGATGTATCAGATTCAGCTACTAGTGACTCAACAAAATCTAAGGGTTCTTGGGGATCTGGA AAGGATCAGTATAGCAGGGAACTGCTTGTGTCCTCCATCTTTGCAGCTGCTAGTCGCAAGAGGAAGAAGC CGAAAGAAAAAGCACAGCCTAGCAGCTCAGAAGATGAACTGGACAATGTATTTTTTAAGAAAGAAAATGT GGAACAGTGTCACAATGATACTAAAGAGGAGTCCAAAAAAGAAAGTGAGACACTGGGCAGAAAACAGAAG ATCATCATTGCCAAAGAAAACAGCACTAGGAAAGACCCCAGCACGACAAAAGATGAAAAGATATCACTAG GAAAAGAGAGCACGCCTTCTGAAGAACCCTCACCACCACACAACTCAAAACACAACAAGTCACCAACTCT CAGCTGTCGCTTTGCCATCCTGAAAGAGAGCCCCAGGTCACTTCTGGCACAGAAGTCCTCCCACCTTGAA GAGACAGGCTCTGACTCTGGCACTTTGCTCAGCACGTCTTCCCAGGCCTCCCTGGCAAGGTTTTCCATGA AGAAATCAACCAGTCCAGAAACGAAACATAGCGAGTTTTTGGCCAACGTCAGCACCATCACCTCAGATTA TTCCACCACATCGTCTGCTACATACTTGACTAGCCTGGACTCCAGTCGACTGAGCCCTGAGGTGCAATCC GTGGCAGAGAGCAAGGGGGACGAGGCAGATGACGAGAGAAGCGAACTCATCAGTGAAGGGCGGCCTGTGG AAACCGACAGCGAGAGCGAGTTTCCCGTGTTCCCCACAGCCTTGACTTCAGAGAGGCTTTTCCGAGGAAA ACTGCAAGAAGTGACTAAGAGCAGCCGGAGAAATTCTGAAGGAAGTGAATTAAGTTGCACCGAGGGAAGT TTAACATCAAGTTTAGATAGCCGGAGACAGCTCTTCAGTTCCCATAAACTCATCGAATGTGATACTCTTT CCAGGAAAAAATCAGCTAGATTCAAGTCAGATAGTGGAAGTCTAGGAGATGCCAAGAATGAGAAAGAAGC ACCTTCGTTAACTAAAGTGTTTGATGTTATGAAAAAAGGAAAGTCAACTGGGAGTTTACTGACACCCACC AGAGGCGAATCCGAAAAACAGGAACCCACATGGAAAACGAAAATAGCAGATCGGTTAAAACTGAGACCCA GAGCCCCTGCGGATGACATGTTTGGAGTAGGGAATCACAAAGTGAATGCCGAGACTGCTAAAAGGAAAAG CATCCGGCGCAGACATACACTAGGAGGGCACAGAGATGCTACCGAAATCAGCGTTTTGAATTTTTGGAAA GTGCATGAGCAGAGCGGGGAGAGAGAATCTGAACTTTCAGCTGTAAACCGGTTAAAACCAAAATGCTCAG CCCAGGACCTTTCCATCTCAGACTGGCTGGCCAGGGAACGCCTACGCACCAGTACCTCTGACCTTAGCAG AGGAGAAATCGGAGATCCCCAGACAGAGAACCCAAGCACACGAGAAATAGCCACGACCGACACACCTTTG TCTCTTCATTGCAACACAGGCAGTTCTTCCAGCACCTTGGCTTCAACAAACAGGCCCCTTCTTTCCATAC CACCACAGTCACCTGACCAAATAAACGGAGAAAGCTTCCAGAACGTGAGCAAAAATGCTAGTTCTGCAGC GAATGCCCAACCTCATAAACTGTCTGAAACCCCAGGCAGTAAAGCAGAGTTTCATCCCTGTCTTTAA
Translation (1958 aa): MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGFGFTLRHFIVY PPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQV IALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEAYSGNARNIPEPPPICYPWLPSA PSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEK VVDLLSNRNNHTGPSHRTEEVRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGN YSGHSDGISSSRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSFSN HRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQEIHKSFRGSNFTV APSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLPRGISQDRSPLVKVRSNSLKAPS THVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENA GTSDLELPVSQRNQDLSLQEAETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTT CWLPNDARREVHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIAD SQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQT TPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTIQESSNLNEEDTGVTN RDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDK GTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNA AISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVET LIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSKGSWGSG KDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVEQCHNDTKEESKKESETLGRKQK IIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLE ETGSDSGTLLSTSSQASLARFSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQS VAESKGDEADDERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLTPT RGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHRDATEISVLNFWK VHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRGEIGDPQTENPSTREIATTDTPL SLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
|