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Report for CCDS5817.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
5817.2 Public Homo sapiens 7 CPA2 24 110 108 CCDS HistoryNCBI Gene:1358Re-query CCDS DB by CCDS ID:5817.2See the combined annotation on chromosome 7 in Sequence Viewer

Public Note for CCDS 5817.1
The coding region has been updated to extend the N-terminus to one that is more supported by available transcript data. Two possible start codons are present in this update, with both start codons having moderately weak Kozak signals. The upstream AUG codon, as represented in this update, is specific to higher primate species, while the downstream AUG is more widely conserved. Due to leaky scanning by ribosomes, it is possible that some ribosomes may initiate translation from the upstream AUG codon while others start from the downstream AUG. Translation initiation from the downstream AUG would result in a protein that is 2 aa shorter at the N-terminus.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)

Sequence IDs included in CCDS 5817.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000222481.9 ENSP00000222481.4 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000222481.9Link to Ensembl Protein Viewer:ENSP00000222481.4Re-query CCDS DB by Nucleotide ID:ENST00000222481Re-query CCDS DB by Protein ID:ENSP00000222481
Original member Current member NCBI NM_001869.3 NP_001860.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_001869.3Link to Protein Sequence:NP_001860.2Re-query CCDS DB by Nucleotide ID:NM_001869Re-query CCDS DB by Protein ID:NP_001860Link to BLAST:NP_001860.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_001860.2 419 P48052 419 100% 0 0

Chromosomal Locations for CCDS 5817.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '+' strand of Chromosome 7 (NC_000007.14)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7See the combined annotation on chromosome 7 in Sequence Viewer

Chromosome Start Stop Links
7 130266882 130266952 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130268929 130269010 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130269669 130269803 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130270693 130270788 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130273076 130273177 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130275149 130275247 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130276628 130276738 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130277826 130277916 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130279463 130279662 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130282104 130282188 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7
7 130289560 130289747 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 7Link to Ensembl Genome Browser on chromosome 7

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1260 nt):
ATGGCCATGAGGTTGATCCTGTTTTTTGGTGCCCTTTTTGGGCATATCTACTGTCTAGAAACATTTGTGG
GAGACCAAGTTCTTGAGATTGTACCAAGCAATGAAGAACAAATTAAAAATCTGCTACAATTGGAGGCTCA
AGAACATCTCCAGCTTGATTTTTGGAAATCACCCACCACCCCAGGGGAGACAGCCCACGTCCGAGTTCCC
TTCGTCAACGTCCAGGCAGTCAAAGTGTTCTTGGAGTCCCAGGGAATTGCCTATTCCATCATGATTGAAG
ACGTGCAGGTCCTGTTGGACAAAGAGAATGAAGAAATGCTTTTTAATAGGAGAAGAGAACGGAGTGGTAA
CTTCAATTTTGGGGCCTACCATACCCTGGAAGAGATTTCCCAAGAAATGGATAACCTCGTGGCTGAGCAC
CCTGGTCTAGTGAGCAAAGTGAATATTGGCTCTTCTTTTGAGAACCGGCCTATGAACGTGCTCAAGTTCA
GCACCGGAGGAGACAAGCCAGCTATCTGGCTGGATGCTGGGATCCATGCTCGAGAGTGGGTTACACAAGC
TACGGCACTTTGGACAGCAAATAAGATTGTTTCTGATTATGGAAAGGACCCATCCATCACTTCCATTCTG
GATGCCCTGGATATCTTCCTCCTGCCAGTCACAAACCCTGATGGATACGTGTTCTCTCAAACCAAAAATC
GTATGTGGCGGAAGACCCGGTCCAAGGTATCTGGAAGCCTCTGTGTTGGTGTGGATCCTAACCGGAACTG
GGATGCAGGTTTTGGAGGACCTGGAGCCAGCAGCAACCCTTGCTCTGATTCATACCACGGACCCAGTGCC
AACTCTGAAGTTGAAGTGAAATCCATAGTGGACTTCATCAAGAGTCATGGAAAAGTCAAGGCCTTCATTA
CCCTCCACAGCTATTCCCAGCTGCTGATGTTCCCCTATGGGTACAAATGTACCAAGTTAGATGACTTTGA
TGAGCTGAGTGAAGTGGCCCAAAAGGCTGCCCAATCTCTGAGAAGCCTGCATGGCACCAAGTACAAAGTG
GGACCAATCTGCTCTGTCATCTACCAAGCCAGTGGAGGAAGCATTGACTGGTCCTATGATTATGGCATCA
AGTACTCATTTGCCTTTGAACTGAGAGACACAGGGCGCTACGGCTTCCTCTTGCCAGCCCGTCAGATCCT
GCCCACAGCCGAGGAGACCTGGCTTGGCTTGAAGGCAATCATGGAGCATGTGCGAGACCACCCCTATTAG

Translation (419 aa):
MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVP
FVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEH
PGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSIL
DALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSA
NSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKV
GPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY


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