NCBI CCDS banner
PubMed Entrez Gene BLAST OMIM
The CCDS database will be unavailable on Tuesday, January 28, 2025, starting at 8:00 a.m. EST for up to 60 minutes.
  

CCDS
Home
FTP
Process
Releases & Statistics

Collaborators
EBI
HGNC
MGI
NCBI

Contact Us
email CCDS

Genome Displays

Ensembl
NCBI
UCSC
VEGA

Related Resources
Gene
HomoloGene
MANE
RefSeq


Report for CCDS8337.2 (current version)

CCDS Status Species Chrom. Gene CCDS Release NCBI Annotation Release Ensembl Annotation Release Links
8337.2 Public Homo sapiens 11 ALKBH8 24 110 108 CCDS HistoryNCBI Gene:91801Re-query CCDS DB by CCDS ID:8337.2Re-query CCDS DB by GeneID:91801See the combined annotation on chromosome 11 in Sequence Viewer

Public Note for CCDS 8337.1
The coding region has been updated to represent an alternative splice pattern, resulting in a longer C-terminus that is more supported by the available transcript and protein data. The update extends a predicted alkylated DNA repair protein domain and adds a C-terminal S-adenosylmethionine-dependent methyltransferase domain to the protein.

Public since: CCDS release 1, NCBI annotation release 35.1, Ensembl annotation release 23

Review status: Reviewed (by RefSeq, Havana and CCDS collaboration)


Attributes
CDS uses downstream AUG

Sequence IDs included in CCDS 8337.2

Original Current Source Nucleotide ID Protein ID MANE Status in CCDS Seq. Status Links
Original member Current member EBI ENST00000389568.7 ENSP00000374219.3 Accepted alive Link to Ensembl Transcript Viewer:ENST00000389568.7Link to Ensembl Protein Viewer:ENSP00000374219.3Re-query CCDS DB by Nucleotide ID:ENST00000389568Re-query CCDS DB by Protein ID:ENSP00000374219
Original member Current member EBI ENST00000417449.6 ENSP00000397673.3 Accepted alive Link to Ensembl Transcript Viewer:ENST00000417449.6Link to Ensembl Protein Viewer:ENSP00000397673.3Re-query CCDS DB by Nucleotide ID:ENST00000417449Re-query CCDS DB by Protein ID:ENSP00000397673
Original member Current member EBI ENST00000428149.7 ENSP00000415885.2 MANE Select Accepted alive Link to Ensembl Transcript Viewer:ENST00000428149.7Link to Ensembl Protein Viewer:ENSP00000415885.2Re-query CCDS DB by Nucleotide ID:ENST00000428149Re-query CCDS DB by Protein ID:ENSP00000415885
Original member Current member NCBI NM_001301010.3 NP_001287939.2 Accepted alive Link to Nucleotide Sequence:NM_001301010.3Link to Protein Sequence:NP_001287939.2Re-query CCDS DB by Nucleotide ID:NM_001301010Re-query CCDS DB by Protein ID:NP_001287939Link to BLAST:NP_001287939.2
Original member Current member NCBI NM_138775.3 NP_620130.2 MANE Select Accepted alive Link to Nucleotide Sequence:NM_138775.3Link to Protein Sequence:NP_620130.2Re-query CCDS DB by Nucleotide ID:NM_138775Re-query CCDS DB by Protein ID:NP_620130Link to BLAST:NP_620130.2

RefSeq Length Related UniProtKB/SwissProt Length Identity Gaps Mismatches
NP_001287939.2 664 Q96BT7-1 664 100% 0 0
NP_620130.2 664 Q96BT7-1 664 100% 0 0

Chromosomal Locations for CCDS 8337.2

Assembly GRCh38.p14 (GCF_000001405.40)

On '-' strand of Chromosome 11 (NC_000011.10)
Genome Browser links: Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11See the combined annotation on chromosome 11 in Sequence Viewer

Chromosome Start Stop Links
11 107504658 107505215 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107510887 107511036 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107522299 107522555 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107525441 107525592 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107532300 107532406 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107549753 107549823 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107551808 107551912 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107553108 107553203 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107553847 107553978 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107556766 107557003 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11
11 107560765 107560893 Link to NCBI NucleotideLink to UCSC Genome Browser on chromosome 11Link to Ensembl Genome Browser on chromosome 11

CCDS Sequence Data
Blue highlighting indicates alternating exons.
Red highlighting indicates amino acids encoded across a splice junction.
 
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair.

Nucleotide Sequence (1995 nt):
ATGGACAGCAACCATCAAAGTAATTACAAACTCAGTAAAACTGAGAAGAAGTTCTTAAGGAAACAGATTA
AAGCCAAGCATACTTTGCTGAGACATGAAGGCATTGAGACAGTATCCTATGCCACTCAGAGCCTGGTTGT
TGCCAATGGTGGTTTGGGTAATGGTGTGAGTCGGAACCAGCTGCTCCCGGTTTTAGAGAAATGTGGACTG
GTGGATGCTCTCTTAATGCCACCTAACAAGCCGTACTCATTTGCAAGATACAGAACTACAGAAGAATCTA
AGAGAGCCTATGTTACCCTCAATGGAAAAGAAGTAGTGGATGATTTAGGACAAAAGATCACTCTGTATTT
GAATTTTGTGGAAAAAGTGCAGTGGAAGGAGTTGAGGCCTCAAGCCTTACCACCAGGACTCATGGTAGTA
GAAGAAATAATTTCTTCTGAGGAGGAGAAAATGCTTTTGGAAAGTGTTGATTGGACAGAAGATACAGACA
ATCAAAACTCTCAAAAATCCTTAAAACACAGAAGAGTAAAGCATTTTGGTTATGAGTTCCACTATGAGAA
CAACAATGTAGATAAAGATAAGCCATTATCTGGGGGTCTTCCTGACATTTGTGAAAGCTTTTTGGAGAAA
TGGTTGAGGAAAGGTTACATTAAACATAAACCTGATCAAATGACCATAAATCAGTATGAACCTGGGCAAG
GAATTCCCGCTCATATTGATACACATTCCGCTTTTGAGGATGAGATCGTTTCTCTCAGTTTGGGGTCAGA
GATTGTCATGGATTTTAAGCACCCAGATGGCATTGCAGTGCCAGTTATGTTGCCTCGTCGGAGTTTGCTG
GTGATGACAGGAGAATCTAGATACCTTTGGACCCATGGAATCACGTGCAGAAAATTTGATACTGTTCAAG
CATCTGAGAGTCTTAAAAGTGGAATTATCACCAGTGATGTTGGAGACTTAACTTTAAGCAAGAGGGGACT
ACGAACATCATTTACATTTAGGAAAGTGAGGCAAACACCTTGTAACTGTAGTTACCCGTTGGTCTGTGAT
AGCCAGAGGAAAGAGACTCCCCCCTCATTTCCAGAGAGTGATAAAGAAGCCTCACGGCTGGAGCAAGAGT
ACGTCCATCAGGTTTATGAAGAGATTGCTGGGCACTTCAGCAGCACAAGACATACCCCTTGGCCGCACAT
TGTGGAGTTTTTGAAGGCTTTGCCAAGTGGTTCAATAGTGGCTGATATTGGATGTGGTAATGGAAAGTAT
CTTGGCATCAATAAGGAGTTATATATGATTGGTTGTGATCGTAGCCAAAACCTTGTGGACATTTGTAGAG
AGAGGCAATTTCAGGCTTTTGTCTGTGATGCATTGGCAGTACCAGTCCGCAGTGGGTCTTGTGATGCCTG
CATCTCCATTGCTGTTATTCATCATTTTGCAACAGCAGAGCGTAGAGTGGCAGCTCTCCAAGAAATTGTT
CGACTCCTGAGACCAGGTGGGAAGGCACTCATTTATGTCTGGGCAATGGAACAAGAATATAATAAGCAGA
AGTCCAAGTATCTTAGAGGAAACAGAAATAGCCAAGGAAAGAAAGAGGAGATGAACAGTGATACCTCAGT
GCAGAGGTCACTTGTGGAGCAAATGCGTGACATGGGCAGTCGAGACTCGGCATCTTCTGTCCCCCGCATT
AATGACTCTCAGGAAGGAGGATGTAATTCAAGGCAAGTTTCTAATTCCAAGCTGCCTGTTCATGTTAACA
GGACTTCTTTTTATTCTCAAGATGTACTGGTTCCCTGGCACCTTAAGGGAAATCCTGATAAAGGCAAACC
TGTTGAGCCATTTGGTCCCATAGGATCCCAGGACCCAAGTCCTGTGTTTCATCGTTACTACCATGTGTTC
CGTGAGGGAGAACTGGAAGGTGCCTGCAGGACTGTGAGTGATGTCAGAATTCTGCAAAGCTACTACGATC
AAGGAAACTGGTGTGTGATTCTTCAAAAGGCCTGA

Translation (664 aa):
MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQLLPVLEKCGL
VDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFVEKVQWKELRPQALPPGLMVV
EEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEK
WLRKGYIKHKPDQMTINQYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLL
VMTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCD
SQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKY
LGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAERRVAALQEIV
RLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRI
NDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVF
REGELEGACRTVSDVRILQSYYDQGNWCVILQKA


Links Key
 Links to:   History report
  BLAST report
  Entrez Gene
  Nucleotide report
  Protein report
 Re-query CCDS DB by:   CCDS ID
  Gene ID
  Nucleotide ID
  Protein ID
 Genome Browser Links:   Ensembl Genome Browser
  NCBI Sequence Viewer
  UCSC Genome Browser
  VEGA Genome Browser

Disclaimer | Write to the Help Desk
NCBI | NLM | NIH