Supplementary material

“Adaptations of the helix-grip fold for ligand binding and catalysis in the START domain superfamily.”

Iyer LM, Koonin EV, Aravind L : Proteins. 2001 May 1;43(2):134-44.

 Bacillus subtilis 
Gene name  gi Domain Domain organization
YndB  7459778 CAS S
 
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 Deinococcus radiodurans
Gene name  gi Domain Domain organization
DRA0006  7471394 CAS S
DR0721  7471434 CAS S
DR2377  7471642 CAS S
DR2247  7472047 CAS S
 
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 Synechocystis PCC6803 
Gene name  gi Domain Domain organization
slr1634  7469466 CAS S
sll0436  7469794 CAS S
 
 
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 Mycobacterium tuberculosis
Gene name  gi Domain Domain organization
Rv0088  7476190 CAS S
Rv0164  7476224 CAS S
Rv0369c  7476329 CAS S + transmembrane
Rv0576  7478993 YS HTH + S + X
Rv0854  7476528 CAS S
Rv0856  7476529 CAS S
Rv0857  7476530 CAS S
Rv0910  7476557 CAS S
Rv1060  7476616 CAS S
Rv1546  7476812 CAS S
Rv1883c  7476949 CAS S
Rv1919c  7476965 CAS S
Rv2185c  7477102 CAS S
Rv2186c  7477103 CAS S
Rv2574  7477263 CAS S
Rv2778c  7477365 CAS S
Rv3076  7477480 CAS S
Rv3718c  7477737 CAS S
 
 
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 Streptomyces coelicolor
 
Gene name  gi Domain Domain organization
2SCG18.30c  9368931 CAS S
Act VII  729280  CAS 2*S
SC10G8.08  7160097 CAS S
SC1E6.13  7479390 CAS S
SC6G10.02c  7479687 CAS S
SC7C7.14  7479744 CAS S
SC9C7.18  7479193 CAS S
SCE20.30  6689189 CAS S
SCG20A.07  8894816 CAS S
SCH10.30c  7480019 CAS S
SCH35.36c  7480053 CAS S
SCL2.25c  6822231 CAS S
WhiE  118111    CAS S
 
 
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 Other Streptomycetes
 
Gene name  gi Domain Domain organization
TcMN  730913  CAS  2*S+Methyltransferase
Griseusin polyketide cyclase  1076098 CAS  2*S
Daunorubicin biosynthesis  7800662 CAS  2*S+small subunit of aromatic oxygenase
AknE1  729279  CAS  2*S
Graniticin polyketide synthase  140718  CAS  2*S
MtmQ  2147731 CAS  2*S
 
 
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 Pseudomonas aeruginosa
Gene name  gi Domain Domain organization
PA1579  9947542 CSD  S
PA2122  9948137 CAS  4*Transmembrane+ S
PA4767  6226458 CAS  S
 
 
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 Rickettsia prowasekii 
Gene name  gi Domain Domain organization
RP166  6226335 CAS  S
 
 
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 Neisseria meningitidis MC58
Gene name  gi Domain Domain organization
NMB0797  7226030 CAS  S
 
 
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 Neisseria meningitidis Z2491
Gene name  gi Domain Domain organization
NMA1006  7379708 CAS  S
 
 
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 Escherichia coli  
Gene name  gi Domain Domain organization
B2619/YfjG  1723618 CAS  S
 
 
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 Vibrio cholerae 
Gene name  gi Domain Domain organization
YfjG  9655301 CAS  S
 
 
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 Xylella fastidiosa  
Gene name  gi Domain Domain organization
XF2347  9107521 CAS  S
 
 
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 Aeropyrum pernix 
Gene name  gi Domain Domain organization
APE2225  5105925 CAS  S
 
 
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 Sulfolobus spp
Gene name  gi Domain Domain organization
ORF-c39_017  6015670 CAS  S
 
 
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 Caenorrhabditis elegans
Gene name  gi Domain Domain organization
C01G10.8  7495122 YS  HCH1 + S
R144.3  7506731 CAS  X + 2* C2H2 + S (possible artificial fusion)
F52F12.7  7503968 CSD  S
K02D3.2  7505123 CSD  S
F25H2.6  7499832 CSD  PH-S
F45H7.2  7503504 CSD  Rhogap-S
F45H7.3  7503505 CSD  Rhogap-S
C06H2.2  7495576 CSD  S
T28D6.7  3880324 CSD  S
F26F4.4  7499948 CSD  transmembrane + S
 
 
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 Drosophila melanogaster
Gene name  gi Domain Domain organization
CG1416  7302133 YS  HCH1 + S
CG9410  7302281 CAS  S
CG6310  7294774 CAS  S
CG6565  7298051 CSD  S
GH07688  7295129 CSD  PH + S
CG8480  7299877 CSD  Rhogap+ S
CG3522  7291812 CSD  2*S
 
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 Homo sapiens
Gene name  gi Domain Domain organization
C14ORF3  6912280 YS  HCH1 + S 
From unannotated   CAS  S 
human genome 
sequence(
ortholog of 
SPCC16A11.07) 
StAR  1351124 CSD  S
GABP  4835895 CSD  PH + S
DLC-1  2654198 CSD  SAM + RhoGAP + S
KIAA0189  1663692 CSD  RhoGAP + S 
KIAA0707  3327228 CSD  2* Thioesterase + S 
MLN64  2135214 CSD  S
KIAA1300  7242955 CSD  S
PPCT  6049276 CSD  S
RhoGAP  4902678 CSD  RhoGAP + S 
CGI-52  4929573 CSD  S
GTT1  8926223 CSD  S
DKFZp434G2416  6807776 CSD  S
From unannotated   CSD  S
human genome 
sequence 
 
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 Saccharomyces cerevisiae
Gene name  gi Domain Domain organization
Ydr214wp  6320420 YS  HCH1+ S 
Yol008wp  6324566 CAS  S
 
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 Schizosaccharomyces pombe
Gene name  gi Domain Domain organization
SPBC1711.08  7630166 YS  HCH1+ S 
SPCC16A11.07  7491835 CAS  S
 
 
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  Arabidopsis thaliana
Gene name  gi Domain Domain organization
T21B14.13  10092489 YS HCH1+S
AT4g17650  7485112 CAS  S-Truncated
T6K21.50  7487778 BA  S
At2g38310  3395441 BA  S
T15B16.3  7487023 BA  S
At2g40330  4586050 BA  S
F3I3.40  7486358 BA  S
At2g26040  3413709 BA  S
T13J8.30  7486961 BA  S
F3N23.20  5903089 BA  S
F28A21.30  7486274 BA  S
At2g25770  3643606 BA  S
F10B6.35  8778221 BA  4*S
F15H11.8  5902396 BA  2*S
F15H11.12  5902402 BA  S
major   1592683 BA  S
latex 
homologue type2 
major   2129641 BA  S
latex 
protein type 1 
T26J12.10  2829899 BA  S
F9D16.140  7448091 BA  S
T16I18.80  7487080 BA  S
F17F8.20  4982514 BA  S
T26J12.11  2829900 BA  S
At2g27670  3860265 PS  S
F5O8.7  4056434 PS  S
F5O8.8  4056435 PS  S
F5O8.12  4056439 PS  S
F5O8.13  4056440 PS  S
F5O8.14  4056441 PS  S
F5O8.15  4056442 PS  S
F5O8.16  4056443 PS  S
F5O8.17  4056444 PS  S
F5O8.18  4056445 PS  S
F5O8.19  4056446 PS   S
F5O8.20  4056447 PS   S
F5O8.21  4056448 PS   S
F5O8.22  4056449 PS   S
F5O8.24  4056450 PS   S
F5O8.23  4056451 PS   S
F24J13.5  6175140 PS   S
T1J1.3  4325343   CSD   HD + S
ovule-specific   2129662 CSD   HD + S
homeotic 
protein homolog 
A20 
YUP8H12.16  2388574 CSD   HD + S
T20K12.50  6850882 CSD   HD + S
Anthocyanine-  5702094 CSD   HD + S
less 2 
At2g32370  3831459 CSD   HD + S
T17B22.5  6714433 CSD   HD + S
probable   7446301 CSD   HD + S
GLABRA2 
F21H2  5668786 CSD   HD + S
ATHB-10/GLABRA2  2129609 CSD   HD + S
M7J2.100  7446302 CSD   HD + S
T28J14_200  7546704 CSD   S
AT4g26920  7269545 CSD   S
ATHB-14  3132474 CSD   HD + S
ATHB-9  2145358 CSD   HD + S
Revoluta  7229679 CSD   HD + S
T16I18.90  7488380 CSD   HD + bZip + S
ATHB-8  4220462 CSD   HD + bZip + S
MXC7.11  9294197 CSD   Transmembrane + S 
Uncharacterized  7485064 CSD   S
 
 
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 Plasmodium spp.
Gene name  gi Domain Domain organization
C0360w  7494197 YS   HCH1+S